When [ATP] is high and in excess, phosphocreatine (PCr) is made as an energy reservoir in muscle and brain that require bursts of energy. Creatine (Cr) + ATP-4   ⇄   PCr-2 + ADP-3 + H+   (near equilibrium) When a sudden demand for energy depletes ATP, the PCr reservoir

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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When [ATP] is high and in excess, phosphocreatine (PCr) is made as an energy reservoir in muscle and brain that require bursts of energy.

Creatine (Cr) + ATP-4   ⇄   PCr-2 + ADP-3 + H+   (near equilibrium)

When a sudden demand for energy depletes ATP, the PCr reservoir is used to replenish ATP. One may ask why the body does not store ATP at higher concentrations and rather store excessive energy in the form of PCr. Since many enzymes are activated or inhibited by higher [ATP], excessive ATP cannot be stored inside of the cells. Looking at the above reaction equation, discuss an advantage of using PCr as the energy reservoir

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