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Signaling molecules interact with cells through specific macromolec- ular receptors. For each of the four receptors identified below, list all characteristics, by number, which accurately describe that receptor. (a) an adrenergic receptor (b) a steroid receptor . (c) the LDL. receptor_ (d) the insulin receptor 1. Located at the cell surface 2. Associated with the protein clathrin 3. Ligand binding stimulates the activity of phospholipase C 4. A transmembrane protein 5. A DNA-binding protein 6. Located in the cell interior 7. Receptor-ligand complex moves to the lysosome 8. Receptor-ligand complex becomes concentrated in the nucleus 9. Receptor activation can inhibit the synthesis of glycogen 10. The hormone-receptor complex activates specific gene tran- scription 11. Internalization decreases the synthesis of cholesterol esters 12. Action of this receptor diminishes the synthesis and activity of B-hydroxy-B-methylglutaryl-CoA reductase (HMG-COA reductase) 13. This receptor activates its own synthesis 14. Biological activity of this receptor involves interaction with guanine nucleotide-binding proteins 15. This receptor has a protein kinase activity 16. Not known to act through a second messenger

Signaling molecules interact with cells through specific macromolec- ular receptors. For each of the four receptors identified below, list all characteristics, by number, which accurately describe that receptor. (a) an adrenergic receptor (b) a steroid receptor . (c) the LDL. receptor_ (d) the insulin receptor 1. Located at the cell surface 2. Associated with the protein clathrin 3. Ligand binding stimulates the activity of phospholipase C 4. A transmembrane protein 5. A DNA-binding protein 6. Located in the cell interior 7. Receptor-ligand complex moves to the lysosome 8. Receptor-ligand complex becomes concentrated in the nucleus 9. Receptor activation can inhibit the synthesis of glycogen 10. The hormone-receptor complex activates specific gene tran- scription 11. Internalization decreases the synthesis of cholesterol esters 12. Action of this receptor diminishes the synthesis and activity of B-hydroxy-B-methylglutaryl-CoA reductase (HMG-COA reductase) 13. This receptor activates its own synthesis 14. Biological activity of this receptor involves interaction with guanine nucleotide-binding proteins 15. This receptor has a protein kinase activity 16. Not known to act through a second messenger

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Signaling molecules interact with cells through specific macromolec- ular receptors. For each of the four receptors identified below, list all characteristics, by number, which accurately describe that receptor. (a) an adrenergic receptor (b) a steroid receptor . (c) the LDL. receptor_ (d) the insulin receptor 1. Located at the cell surface 2. Associated with the protein clathrin 3. Ligand binding stimulates the activity of phospholipase C 4. A transmembrane protein 5. A DNA-binding protein 6. Located in the cell interior 7. Receptor-ligand complex moves to the lysosome 8. Receptor-ligand complex becomes concentrated in the nucleus 9. Receptor activation can inhibit the synthesis of glycogen 10. The hormone-receptor complex activates specific gene tran- scription 11. Internalization decreases the synthesis of cholesterol esters
Transcribed Image Text:Signaling molecules interact with cells through specific macromolec- ular receptors. For each of the four receptors identified below, list all characteristics, by number, which accurately describe that receptor. (a) an adrenergic receptor (b) a steroid receptor . (c) the LDL. receptor_ (d) the insulin receptor 1. Located at the cell surface 2. Associated with the protein clathrin 3. Ligand binding stimulates the activity of phospholipase C 4. A transmembrane protein 5. A DNA-binding protein 6. Located in the cell interior 7. Receptor-ligand complex moves to the lysosome 8. Receptor-ligand complex becomes concentrated in the nucleus 9. Receptor activation can inhibit the synthesis of glycogen 10. The hormone-receptor complex activates specific gene tran- scription 11. Internalization decreases the synthesis of cholesterol esters
12. Action of this receptor diminishes the synthesis and activity of B-hydroxy-B-methylglutaryl-CoA reductase (HMG-COA reductase) 13. This receptor activates its own synthesis 14. Biological activity of this receptor involves interaction with guanine nucleotide-binding proteins 15. This receptor has a protein kinase activity 16. Not known to act through a second messenger
Transcribed Image Text:12. Action of this receptor diminishes the synthesis and activity of B-hydroxy-B-methylglutaryl-CoA reductase (HMG-COA reductase) 13. This receptor activates its own synthesis 14. Biological activity of this receptor involves interaction with guanine nucleotide-binding proteins 15. This receptor has a protein kinase activity 16. Not known to act through a second messenger
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