82. Regulation of cellular metabolism by insulin requires activation of the insulin-receptor substrate protein-1 (IRS1). Some individuals who have type 2 diabetes mellitus have mutations in the IRS1 gene. Which of the following normal steps in insulin signaling is most likely to be impaired by these mutations? A) Cleavage of IRS1 by the insulin receptor B) Phosphorylation of IRS1 by the insulin receptor C) Production of inositol 1,4,5-trisphosphate by IRS1 OD) Stimulation of a G protein by IRS1 E) Synthesis of diacylglycerol by IRS1

Q: 2. Researchers have discovered significant changes in the gene of some protein, which is a substrate…

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Q: What level of protein structure is hexameric insulin?

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Q: What is role of insulin in human body?

A: Introduction Glucose is the main source of energy and the simplest carbohydrate which is present in…

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Q: Which one of the following statements concerning disorders of muscle metabolism presented in class…

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A: Hormones are chemical messengers and help in the growth and development of organisms. The different…

Q: Name the genetically engineered human Insulin?

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Q: 10. Proinsulin, stored in secretory vesicles in the B-cells of pancreatic islets, is converted to…

A: Proinsulin is a single chain pancreatic polypeptide precursor of the hormone insulin which results…

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A: The excretory system is composed of the kidneys, ureters, urethras and urinary bladders. The…

Q: 32. During a study of insulin response, a healthy nonobese 24-year-old woman consumes four pancakes…

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Q: Describe the effects of The effect on the glucagon response in the liver treated with a cAMP…

A: Glucagon Response in liver: The role of glucagon in the body is to control the blood glucose levels…

Q: During regulation of glycogen synthesis by glucagon, what molecule is the secondary messenger?

A: There are a few important points : Glycogen is a highly branched and very large polymer of glucose…

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A: Introduction : Glucokinase  is a protein that works with phosphorylation of glucose to…

Q: 32. Through our expertise in biochemical manipulation, we found a way to alter the G protein-coupled…

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Q: 64 An investigator is studying the mechanism of action of an insulin-sensitizing drug. The addition…

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Q: Discuss the advantages and disadvantages of using genetic engineering to produce human insulin.

A: ADVANTAGES:- This GM insulin has some advantages over insulin taken from pigs or cattle. it…

Q: Please explain the steps in this pathway on the picture.

A: Glycolysis is an oxidative process in which one mole of glucose is partially oxidized into the two…