Please explain the steps in this pathway on the picture. Regulation of PFK-2/FBPase-2PFK-2↑(F26BP](active)онStimulates glycolysis,inhibits gluconeogenesisFBPase-2(inactive)-ATPCAMP-phospho-proteinphosphatasedependentglucagon(CAMP)insulin -----proteinkinaseH,0ADPPFK-2V(F26BP)(inactive)0-P-0Inhibits glycolysis,stimulates gluconeogenesisFBPase-2(active)Fig. 15-19, page 594

Answered: Please explain the steps in this…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

Please explain the steps in this pathway on the picture.

Regulation of PFK-2/FBPase-2
PFK-2
↑(F26BP]
(active)
он
Stimulates glycolysis,
inhibits gluconeogenesis
FBPase-2
(inactive)
-ATP
CAMP-
phospho-
protein
phosphatase
dependent
glucagon
(CAMP)
insulin -----
protein
kinase
H,0
ADP
PFK-2
V(F26BP)
(inactive)
0-P-0
Inhibits glycolysis,
stimulates gluconeogenesis
FBPase-2
(active)
Fig. 15-19, page 594

Expert Solution

Step 1

Glycolysis is an oxidative process in which one mole of glucose is partially oxidized into the two moles of pyruvate in a series of enzyme-catalyzed reactions. Glycolysis occurs in the cytosol. it is a unique pathway that presents in both aerobic well as anaerobic conditions and does not involve molecular oxygen. Glycolysis is the first major metabolic process of cellular respiration, and it generates ATP as its product. In reality, glycolysis is a component of the metabolism of practically all living species.