Kindly refer to the image and answer the question4. Explain the mechanism of action of the adenyl cyclic system using aschematic diagram. 1 Unoccupied receptor doesnot interact with G, protein.Extra-collularspace-Hormone or neuro-transmitterCellmembraneGs proteinwith bound GDPSynaptic signalingReceptorTargetcellInactive adenylylCytosolGOPcyclaseNervecellOccupied receptor changes2 shape and interacts with asubunit of G, protein. G, proteinreleases GDP and binds GTP.NeurotransmitterEndocrine signalingHormoneInactiveadenylylcyclaseGTPTargetcellGDPa Subunit of G, protein3 dissociates from By andBlood vesselactivates adenylyl cyclase.ActiveadenylylcyclaseDirect contactАТРGapjunctionGTPCAMP + PPWhen hormone is no longer4 present, the receptor revertsto resting state. GTP on thea subunít is hydrolyzed to GDP,a rejoins By, and adenylylcyclase is deactivated.SignalingcellTargetcellsInactiveadenylylcyclase

Metabolic regulation: Energy production or the synthesis of various end products to meet the energy…

Hormone Inactive adenylyl cyclase GTP Target cell GDP Blood vessel a Subunit of G, protein 3 dissociates from By and activates adenylyi cyclase. Active adenylyl cyclase Direct contact ATP Gap junction GTP CAMP + PP When hormone is no longer present, the receptor reverts to resting state. GTP on the a subunit is hydrolyzed to GDP, a rejoins By, and adenylyl cyclase is deactivated. Signaling cell -Target cells Inactive adenylyl cyclase GOP

Hormone Inactive adenylyl cyclase GTP Target cell GDP Blood vessel a Subunit of G, protein 3 dissociates from By and activates adenylyi cyclase. Active adenylyl cyclase Direct contact ATP Gap junction GTP CAMP + PP When hormone is no longer present, the receptor reverts to resting state. GTP on the a subunit is hydrolyzed to GDP, a rejoins By, and adenylyl cyclase is deactivated. Signaling cell -Target cells Inactive adenylyl cyclase GOP

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

Transmission is: O A. conversion of amino acid to hydroxyl acid B. loss of ammonia from amino acids O c. formation of ammonium salt from ammonia OD. conversion of amino acids to keto acids 21
17. Accumulation of high levels of chloramphenicol in newbom that leads to a gray baby syndrome is due to он H .CHCI2 O,N- но chloramphenicol A. Lack of UDP-glucuronosyltransferase B. Renal uptake of metabolized product C. High lipophilicity of chloramphenicol D. Poor absorption of chloramphenicol 16
describe the development of lactose intolerance from child age to adult age. also describe the detailed mechanism and molecular and enzymatic pathway related to development of lactose intolerance.
Which of the followings is/are regulated by proteolytic cleavage? O pepsinogen chymotrypsinogen Trypsinogen All are correct
Click on all gllycosidic bonds in the structure below H OH H_o HO но H. H. H. H_o HO HO CEN H. HO. H. H. Amygdalin from bitter almond seeds and apricot and peach pits Many cancer sufferers went abroad for chemotherapy with amygdalin, called Laetril. Unfortunately, its is ineffective theraputically and highly toxic to all cells owing to indiscrnimınate release of hydrogen cyanide under physiological.conditions 工エ

Well-known compound involved in appetitis control, and formed from tryptophan predominantly by gut microbes is: leukotriene epinephrine serotonin nicotinic acid prostaglandine
Match the water soluble vitamin with its main function. coenzyme specifically with tryptophan metabolism, hemoglobin Choose... DNA, RNA, cell division Choose... thiamin, riboflavin, niacin vitamin C antioxidant, collagen synthesis, redox B12 Folate coenzyme B6 Choose... DNA, RNA, methionine metabolism >
Match to the correct term by dragging-and-dropping the words below: Glucuronidation Hydroxylation Liver/gut mucosa Process of adding hydrophilic group(s) to drug/metabolite molecule, to allow drug/metabolite excretion in the urine Prodrug P glycoprotein Enterohepatic cycling Process converting lipophilic drug to more polar molecule by unmasking or adding a polar functional group Process of forming multiple bonds between molecules and a transition metal ion, leading to sequestration of the metal Drug-nutrient interaction
Please answer abcde in a simple way
8. Give brief information about cystatin C and SDMA. Discuss the pros and cons compared to creatinine.
2. Within a cellular environment, draw the sequence of events that occur when extracellular LDL binds to the LDL receptor through generation of cholesterol. Represent the sequence of events numerically. Label all relevant cellular structures. Details to include: components of the endocytic pathway and the pH of the compartments representation of the LDL binding domain and beta-propeller domain of the LDL receptor. Conformation of LDL receptor Use a "+"to indicate when histidine(s) become protonated on the LDL receptor. V-ATPases
Describe/explain the role of Vit. A (retinol) in animal cells/organs