Kindly refer to the image and answer the question4. Explain the mechanism of action of the adenyl cyclic system using aschematic diagram. 1 Unoccupied receptor doesnot interact with G, protein.Extra-collularspace-Hormone or neuro-transmitterCellmembraneGs proteinwith bound GDPSynaptic signalingReceptorTargetcellInactive adenylylCytosolGOPcyclaseNervecellOccupied receptor changes2 shape and interacts with asubunit of G, protein. G, proteinreleases GDP and binds GTP.NeurotransmitterEndocrine signalingHormoneInactiveadenylylcyclaseGTPTargetcellGDPa Subunit of G, protein3 dissociates from By andBlood vesselactivates adenylyl cyclase.ActiveadenylylcyclaseDirect contactАТРGapjunctionGTPCAMP + PPWhen hormone is no longer4 present, the receptor revertsto resting state. GTP on thea subunít is hydrolyzed to GDP,a rejoins By, and adenylylcyclase is deactivated.SignalingcellTargetcellsInactiveadenylylcyclase

Metabolic regulation: Energy production or the synthesis of various end products to meet the energy…

Hormone Inactive adenylyl cyclase GTP Target cell GDP Blood vessel a Subunit of G, protein 3 dissociates from By and activates adenylyi cyclase. Active adenylyl cyclase Direct contact ATP Gap junction GTP CAMP + PP When hormone is no longer present, the receptor reverts to resting state. GTP on the a subunit is hydrolyzed to GDP, a rejoins By, and adenylyl cyclase is deactivated. Signaling cell -Target cells Inactive adenylyl cyclase GOP

Hormone Inactive adenylyl cyclase GTP Target cell GDP Blood vessel a Subunit of G, protein 3 dissociates from By and activates adenylyi cyclase. Active adenylyl cyclase Direct contact ATP Gap junction GTP CAMP + PP When hormone is no longer present, the receptor reverts to resting state. GTP on the a subunit is hydrolyzed to GDP, a rejoins By, and adenylyl cyclase is deactivated. Signaling cell -Target cells Inactive adenylyl cyclase GOP

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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