Ribosome ER signal sequance As a polypaptde is belng made, SP binds to an ER signal sequence and causes tandationto pauisa SRP SP binds to an SRP receptor in the ER membrane, which is located next to a channel For his binding to ocour, proteins within SRP and the SRP receptor must also be bound by CTP. Cytosol ER membrane ER lumon Channel SRP receptor The GTRbinding proteins within SRP and the SRP recoptor hydrolyze their CTP, Cusing he releaie of SRP. This alows translation toresume, and the polypeptde is threaded trough a channa into the ER umen COPP
Ribosome ER signal sequance As a polypaptde is belng made, SP binds to an ER signal sequence and causes tandationto pauisa SRP SP binds to an SRP receptor in the ER membrane, which is located next to a channel For his binding to ocour, proteins within SRP and the SRP receptor must also be bound by CTP. Cytosol ER membrane ER lumon Channel SRP receptor The GTRbinding proteins within SRP and the SRP recoptor hydrolyze their CTP, Cusing he releaie of SRP. This alows translation toresume, and the polypeptde is threaded trough a channa into the ER umen COPP
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Referring to Figure 18.5, predict what would happen if the SRP
RNA was unable to stimulate the GTPase activities of the GTPbinding
proteins within SRP and the SRP receptor.
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