Quit Smoking: The New England Journal of Medicine published the results of a double-blind, placebo-controlled experiment to study the effect of nicotine patches and the antidepressant bupropion on quitting smoking. The target for quitting smoking was the 8th day of the experiment. In this experiment researchers randomly assigned smokers to treatments. We conducted a hypothesis test to determine if the side effect rates are significantly different for nicotine patches versus bupropion at a 5% level of significance. (The normality conditions are met by the data.) The P-value is 0.04. What can we conclude? We reject the null hypothesis. The side effects are more painful for people taking bupropion. We reject the null hypothesis. The side effect rate for bupropion is significantly higher than the side effect rate for the nicotine patches. We fail to reject the null hypothesis. The side effect rates are different, but not significantly different. We reject the null hypothesis. The side effect rates are significantly different for bupropion and the nicotine patches.

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