Answered: Rogers, Farlow, and colleagues (1998)…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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Rogers, Farlow, and colleagues (1998) conducted an experiment to investigate whether donepezil improved cognitive function in patients with mild to moderate Alzheimer’s disease (AD). A total of 1,775 patients were randomly assigned to treatment with either donepezil or a placebo (a look-alike pill with no pharmacological effect). Cognitive function, as measured by the Alzheimer’s Disease Assessment Scale (ADAS-cog), was significantly improved in patients taking donepezil compared with the placebo group at weeks 12, 18, and 24. [Source: Rogers, S. L., Farlow, M. R., Doody, R. S., et al. (1998). A 24-week, double-blind, placebo controlled trial of donepezil in patients with Alzheimer’s disease. Neurology, 50, 136–145.] In this experiment, the independent variable is , and the dependent variable is . The individuals who are in the control condition are typically referred to as the control group. Here, the control group consists of . is a construct that is being tested in this experiment, and the experimenters have operationally defined it as .

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