Question 1 Which of the following statements is true regarding compounds of the TCA cycle resulting from introduction into the TCA cycle of Glutamate labeled in the R group carboxyl carbon transaminated to a-Ketoglutarate and taken through one complete round back to Succinyl CoA? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V After one complete round Succinyl CoA will be radioactive. The labeled R group carboxyl of Glutamate will be released as radioactive carbon dioxide. The transfer of Acetyl-CoA to Oxaloacetate will be result in radioactive Citric Acid. d. A possible source of radioactive carbon dioxide is the Isocitrate Dehydrogenase reaction. A possible source of radioactive carbon dioxide is the a-Ketoglutarate Dehydrogenase reaction. No released carbon dioxide is radioactive. If taken through two complete rounds Succinyl CoA produced will be radioactive. The carbon of the resulting citric acid bearing the hydroxyl group is oxidized by a-Ketoglutarate Dehydrogenase. i Both of the - CHz- carbons of the formed Succinate are oxidized by Succinate Dehydrogenase
Question 1 Which of the following statements is true regarding compounds of the TCA cycle resulting from introduction into the TCA cycle of Glutamate labeled in the R group carboxyl carbon transaminated to a-Ketoglutarate and taken through one complete round back to Succinyl CoA? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V After one complete round Succinyl CoA will be radioactive. The labeled R group carboxyl of Glutamate will be released as radioactive carbon dioxide. The transfer of Acetyl-CoA to Oxaloacetate will be result in radioactive Citric Acid. d. A possible source of radioactive carbon dioxide is the Isocitrate Dehydrogenase reaction. A possible source of radioactive carbon dioxide is the a-Ketoglutarate Dehydrogenase reaction. No released carbon dioxide is radioactive. If taken through two complete rounds Succinyl CoA produced will be radioactive. The carbon of the resulting citric acid bearing the hydroxyl group is oxidized by a-Ketoglutarate Dehydrogenase. i Both of the - CHz- carbons of the formed Succinate are oxidized by Succinate Dehydrogenase
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Question 1
Which of the following statements is true regarding compounds of the TCA cycle resulting from introduction into the TCA cycle of
Glutamate labeled in the R group carboxyl carbon transaminated to a-Ketoglutarate and taken through one complete round back
to Succinyl CoA?
Multiple answers: Multiple answers are accepted for this question
Select one or more answers and submit. For keyboard navigation. SHOW MORE V
a
After one complete round Succinyl CoA will be radioactive.
b
The labeled R group carboxyl of Glutamate will be released as radioactive carbon dioxide.
The transfer of Acetyl-CoA to Oxaloacetate will be result in radioactive Citric Acid.
d
A possible source of radioactive carbon dioxide is the Isocitrate Dehydrogenase reaction.
e
A possible source of radioactive carbon dioxide is the a-Ketoglutarate Dehydrogenase reaction.
f
No released carbon dioxide is radioactive.
If taken through two complete rounds Succinyl CoA produced will be radioactive.
h
The carbon of the resulting citric acid bearing the hydroxyl group is oxidized by a-Ketoglutarate Dehydrogenase.
i
Both of the - CH2 carbons of the formed Succinate are oxidized by Succinate Dehydrogenase
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