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The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form acetyl CoA. E₁, E2, and E3 are abbreviations for the enzymes of the complex. Classify the enzyme names, prosthetic groups, and reactions as E1, E2, or E3.

The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form acetyl CoA. E₁, E2, and E3 are abbreviations for the enzymes of the complex. Classify the enzyme names, prosthetic groups, and reactions as E1, E2, or E3.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form acetyl CoA. E₁, E2, and E3 are abbreviations for the enzymes of the complex. Classify the enzyme names, prosthetic groups, and reactions as E₁, E2, or E3. E₁ E₂ E3
Transcribed Image Text:The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to form acetyl CoA. E₁, E2, and E3 are abbreviations for the enzymes of the complex. Classify the enzyme names, prosthetic groups, and reactions as E₁, E2, or E3. E₁ E₂ E3
hydroxyethyl group transferred to lipoamide formation of hydroxyethyl-TPP pyruvate dehydrogenase Answer Bank dihydrolipoyl transacetylase dihydrolipoyl dehydrogenase transfer of acetyl group to coenzyme A FAD lipoamide transfer of electrons to FAD and then to NAD thiamine pyrophosphate (TPP)
Transcribed Image Text:hydroxyethyl group transferred to lipoamide formation of hydroxyethyl-TPP pyruvate dehydrogenase Answer Bank dihydrolipoyl transacetylase dihydrolipoyl dehydrogenase transfer of acetyl group to coenzyme A FAD lipoamide transfer of electrons to FAD and then to NAD thiamine pyrophosphate (TPP)
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