Pyruvate dehydrogenase phosphatase is the regulatory component of pyruvatedehydrogenase complex. Pyruvate dehydrogenase phosphatase can remove the phosphorylgroups from the phosphorylated enzymes. Assume that the gene for pyruvate dehydrogenasephosphatase is mutated and the mutated pyruvate dehydrogenase phosphatase completelylose its function. Patients with such a gene mutation exhibit all the symptoms of beriberi. Doyou think beriberi, resulting from the mutations of pyruvate dehydrogenase phosphatase, canbe successfully treated by placing such patients on a thiamine-enriched diet? Briefly explain your reasonings

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Pyruvate dehydrogenase phosphatase is the regulatory component of pyruvatedehydrogenase complex. Pyruvate dehydrogenase phosphatase can remove the phosphorylgroups from the phosphorylated enzymes. Assume that the gene for pyruvate dehydrogenasephosphatase is mutated and the mutated pyruvate dehydrogenase phosphatase completelylose its function. Patients with such a gene mutation exhibit all the symptoms of beriberi. Doyou think beriberi, resulting from the mutations of pyruvate dehydrogenase phosphatase, canbe successfully treated by placing such patients on a thiamine-enriched diet? Briefly explain your reasonings.

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