Put a primer on the top and bottom of bubble at origin. Identify 3’ ends. You can use a thicker line or different color. Primers are short (10-12 nucleotides). Draw two primers on lagging strand. Identify 3’ ends. Draw new DNA strands. Identify 3’ ends. New DNA is at least 10x longer than the primer. You don’t have to draw to scale but make it longer. Remember that the new DNA synthesis begins exactly at the 3’ end of the primer. Do not leave a gap (space) between 3’ end of primer and 5’ end of new DNA. Label leading and lagging strands. PRACTICE this with 5’ at top left and 3’ top left. If you can draw these two bubbles you can draw any of the 4 possible replication forks or any straight line section of DNA replication!

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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  1. Put a primer on the top and bottom of bubble at origin. Identify 3’ ends. You can use a thicker line or different color. Primers are short (10-12 nucleotides).
  2. Draw two primers on lagging strand. Identify 3’ ends.
  3. Draw new DNA strands. Identify 3’ ends. New DNA is at least 10x longer than the primer. You don’t have to draw to scale but make it longer. Remember that the new DNA synthesis begins exactly at the 3’ end of the primer. Do not leave a gap (space) between 3’ end of primer and 5’ end of new DNA.
  4. Label leading and lagging strands.
  5. PRACTICE this with 5’ at top left and 3’ top left. If you can draw these two bubbles you can draw any of the 4 possible replication forks or any straight line section of DNA replication!
 
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