Problem:  A prescription calls for 1% solution pilocarpine (freezing point= -0.14 degrees celsius) to be be made isotonic with tears using sodium chloride.  Questions:  1. What method of tonicity adjustment will be used in the preparation? 2. What is the working formula of the method used in Problem? 3. How many grams of sodium chloride must be added to the Pilocarpine solution to make it isotonic?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Problem: 

A prescription calls for 1% solution pilocarpine (freezing point= -0.14 degrees celsius) to be be made isotonic with tears using sodium chloride. 

Questions: 

1. What method of tonicity adjustment will be used in the preparation?

2. What is the working formula of the method used in Problem?

3. How many grams of sodium chloride must be added to the Pilocarpine solution to make it isotonic?

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