Peak Solution Preparation Area 0.045 g of paracetamol is weighed in a 50 mL volumetric flask and made up to the mark with methanol 0.055 g of paracetamol is weighed in a 50 mL volumetric flask and made up to the mark with methanol. 0.095 g of paracetamol is weighed in a 100 mL volumetric flask and made up to the mark with methanol. 32 mg of paracetamol is weighed in a 250 mL volumetric flask and made up to the mark with methanol. A 8957 9845 10450 D 4500

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter1: Matter, Energy, And Measurement
Section: Chapter Questions
Problem 1.112P: 1-112 A febrile, pediatric patient weighs 42 pounds. You need to administer acetaminophen (Tylenol)...
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Chemistry

The below table shows how the paracetamol standard solutions were prepared for the

method validation and respective peak area obtained in HPLC. The best linear fit of the

calibration curve is y = 5.9999 x + 3821.1 with R2 = 0.9416. Explain why the calibration is

unacceptable and suggest how it can be improved.

Peak
Solution
Preparation
Area
0.045 g of paracetamol is weighed in a 50 mL volumetric flask
and made up to the mark with methanol
0.055 g of paracetamol is weighed in a 50 mL volumetric flask
and made up to the mark with methanol.
0.095 g of paracetamol is weighed in a 100 mL volumetric flask
and made up to the mark with methanol.
32 mg of paracetamol is weighed in a 250 mL volumetric flask
and made up to the mark with methanol.
A
8957
B
9845
C
10450
D
4500
Transcribed Image Text:Peak Solution Preparation Area 0.045 g of paracetamol is weighed in a 50 mL volumetric flask and made up to the mark with methanol 0.055 g of paracetamol is weighed in a 50 mL volumetric flask and made up to the mark with methanol. 0.095 g of paracetamol is weighed in a 100 mL volumetric flask and made up to the mark with methanol. 32 mg of paracetamol is weighed in a 250 mL volumetric flask and made up to the mark with methanol. A 8957 B 9845 C 10450 D 4500
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