ou are studying a caspase cleavage site in an N protein from a new coronavirus you make a D/E site-directed mutation at this cleavage site and find that the Mutant protein is uncleaved during virus-induced apoptosis. Thus the aspartic acid is:  a negative regulator of cleavage  irrelevant for cleavage  necessary for cleavage  sufficient for cleavage

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You are studying a caspase cleavage site in an N protein from a new coronavirus you make a D/E site-directed mutation at this cleavage site and find that the Mutant protein is uncleaved during virus-induced apoptosis. Thus the aspartic acid is: 

a negative regulator of cleavage 

irrelevant for cleavage 

necessary for cleavage 

sufficient for cleavage 

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