|| AB ||| AA 1 0₂ AA AB 2 BB 0₁ In this pedigree A and B represent alleles at a marker locus very closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 (a female of 10 years) is unknown as yet as the disease does not onset until teenage years or soon after. Which of the following is correct? OA. The probable pattern of inheritance shown by the disease in this family is autosomal recessive. OB. If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1. OC. If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1. OD. If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she inherits an AB marker genotype equals 0.96. OE. The probable pattern of inheritance shown by the disease in this family is X-linked recessive.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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||
AB
|||
1
AA
0₂
AA
0₁
In this pedigree A and B represent alleles at a marker locus very closely linked to the disease locus. Affected individuals are shown as
shaded. The disease status in III 1 (a female of 10 years) is unknown as yet as the disease does not onset until teenage years or soon
after. Which of the following is correct?
2
AB
BB
OA. The probable pattern of inheritance shown by the disease in this family is autosomal recessive.
OB. If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1.
OC. If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1.
OD. If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she
inherits an AB marker genotype equals 0.96.
OE. The probable pattern of inheritance shown by the disease in this family is X-linked recessive.
Transcribed Image Text:|| AB ||| 1 AA 0₂ AA 0₁ In this pedigree A and B represent alleles at a marker locus very closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 (a female of 10 years) is unknown as yet as the disease does not onset until teenage years or soon after. Which of the following is correct? 2 AB BB OA. The probable pattern of inheritance shown by the disease in this family is autosomal recessive. OB. If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1. OC. If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1. OD. If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she inherits an AB marker genotype equals 0.96. OE. The probable pattern of inheritance shown by the disease in this family is X-linked recessive.
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