For the following problems, please choose from the following modes of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive ㅇㄱㅁ 입 ㅇㄹ I. What is the most likely mode of inheritance portrayed in the pedigree above?
Q: An unaffected man and an unaffected woman mate and have a son affected with Kakamania. Which of the…
A: Answer: Chromosomal Inheritance is the process of transferring the genetic information from parents…
Q: Identify the mode of inheritance in the pedigree below and indicate the correct genotype of each…
A: Genetics is the study of genes, their interactions, and the effect of the environment on genes.…
Q: Both red/green color blindness (R=normal, r=colorblind) and Duchenne-type muscular dystrophy…
A: X-linked recessive inheritance is the genetic condition that can be passed from parent to child…
Q: Cystic Fibrosis (CF) is an autosomal recessive condition. Therefore, heterozygous (Cc) carriers do…
A: As a hereditary counselor, we would direct them through the probabilities of their children…
Q: his pedigree shows the inheritance of sickle cell diseases. Please fill out the genotypes of the…
A: Answer: Sickle cell anemia is an autosomal recessive disorder which is transferred from parents to…
Q: Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree,…
A: Pedigree is a representation in the form of a diagram or family tree of inheritance of genetic…
Q: In a cross between an individual with Huntington disease and an unaffected individual, what are the…
A: Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional…
Q: What feature(s) of this pedigree indicate(s) dominant inheritance?
A: Huntington's disease is a genetic degenerative neurological disorder which arises because of…
Q: I. II. III. 1 1 2 2 ? 3 3 In the pedigree above, there could be carriers that are not marked. For…
A: PEDIGREE ANALYSIS: The analysis of the diagram or chart that represents a family's genetic history…
Q: The following cross is performed between two varieties of fish that differ in scale color. What…
A: Alleles are the alternative forms of a gene that are located on the same locus of a homologous…
Q: There are two traits not shown in the pedigree: albinism (autosomal recessive) and Marfan syndrome…
A: A pedigree chart is a graphic that depicts the incidence and emergence of phenotypes of a certain…
Q: Hereditary canine spinal muscular atrophy (HCSMA) is a motor neuron disease in Brittany Spaniels.…
A: Hereditary Canine Spinal Muscular Atrophy (HCSMA), a motor neuron disease affecting Brittany…
Q: 6) For the pedigree shown below, answer the following questions. I II II I a) What type of…
A: Pedigree analysis helps us identifying the mode of inheritance of a particular disease by observing…
Q: Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family…
A: Pedigree analysis helps us to understand the mode of inheritance of a particular disease by…
Q: The pedigree below represents the inheritance of a rare genetic disorder (members joining the…
A: The answer is written in explanation box below:Explanation:…
Q: Hypophosphatemia is a dominant genetic disorder caused by a deficiency of phosphates in the blood.…
A: X-linked genetic disorders can either be recessive or dominant. In this example we can conclude that…
Q: 7) The pedigree below traces the inheritance of alkaptonuria, a biochemical disorder. Does…
A: A pedigree is a chart that shows how a trait is inherited, identifying the afflicted and normal…
Q: Below is a pedigree chart for a family that has a history of Alkaptonuria. Individuals infected…
A: Pedigree analysis is a method to identify the inheritance of a genetic trait across generations.…
Q: A) Determine the type of inheritance shown on this pedigree. Explain your answer. B) Based on your…
A: Ans - Considering Genotype detention as D - for not having disease allele and d- for having…
Q: Pedigree attached shows an autosomal recessive genetic disease. G is the normal allele and g is the…
A: The pedigree study helps us to make conclusion about the inheritance pattern and probability of…
Q: What is the mode of inheritance for the genes controlling maniac and shiny? autosomal dominant for…
A: Mutation A kind of alteration in the DNA base pairs either by chemical or physical or by some error…
Q: In each of the following pedigrees (C, D) by inspection, determine the mode of inheritance involved.…
A: A pedigree is a graph that shows a family's genetic history over numerous generations. Women are…
Q: The pedigree shows inheritance of the autosomal recessive trait cystic fibrosis in a family. Family…
A: Diploid organisms carry two sets of chromosomes and thus, carry two copies of almost every gene.…
Q: Consider the pedigree below for the hairy toes trait, denoted with the gene symbols H and h (if…
A: A pedigree is a representation of the inheritance of a trait or character or disease from one…
Q: This pedigree shows the segregation of a rare disease in a family. What is the most likely mode of…
A: Answer: PEDIGREE CHART : It is the genetic chart of the generations which is used to study the…
Q: Filled (red) circles represent affected females. Filled (red) squares represent affected males.…
A: Pedigree is the analysis of a disease in the family history that gives us an idea about the…
Q: he family is shown in both pedigrees below. Each pedigree focuses on a different monogenic, fully…
A: X linked recessive trait- this trait is associated with mutations in genes on the X chromosome. As…
Q: The pedigree below shows a family with a history of an autosomal recessive genetic disease with one…
A: Pedigree analysis is a family chart used to study the inheritance pattern of traits or diseases…
Q: A mother is heterozygous for the X-linked gene for colorblindness and also heterozygous for the…
A: Genes controls the genetic characteristics of an organism. The genes have two alleles that…
Step by step
Solved in 2 steps
- Regarding Mendelian inheritance in diploid individuals, (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) a diploid individual receives two copies of every autosome from the previous generation. for every autosomal gene inherited by an individual, both copies can come from one parent. a diploid individual gives two copies of every autosome to a child in the next generation. to be diploid means that two independent genes are specified in the individual's genotype.The following pedigree shows the pattern of inheritance of red-green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in black. What is the chance that a son of the third-generation female indicated by the arrow will be color blind if the father is not color blind? If he is color blind?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?
- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?For the following diseases with their potential pedigree, mode of inheritance and the responsible gene: (Pedigrees A, B, and C) -> Do Pedigree B Pedigree B, Autosomal dominant, Huntingtin gene Pedigree B, Autosomal dominant, CFTR gene Pedigree B, Autosomal dominant, HexA gene Pedigree B, Autosomal dominant, FGFR3 gene Pedigree A, Autosomal recessive, CFTR gene Pedigree A, Autosomal recessive, Beta-globin gene Pedigree A, Autosomal dominant, FGFR3 gene Pedigree B, X-linked dominant. Factor VIII gene Pedigree A, Autosomal dominant, Beta-globin gene Pedigree A. Autosomal recessive, Huntingtin gene Pedigree C, X-linked recessive, Factor VIII gene Pedigree A, Autosomal recessive, HexA gene
- For the following diseases with their potential pedigree, mode of inheritance and the responsible gene: (Pedigrees A, B, and C) -> Do Pedigree A Pedigree B, Autosomal dominant, Huntingtin gene Pedigree B, Autosomal dominant, CFTR gene Pedigree B, Autosomal dominant, HexA gene Pedigree B, Autosomal dominant, FGFR3 gene Pedigree A, Autosomal recessive, CFTR gene Pedigree A, Autosomal recessive, Beta-globin gene Pedigree A, Autosomal dominant, FGFR3 gene Pedigree B, X-linked dominant. Factor VIII gene Pedigree A, Autosomal dominant, Beta-globin gene Pedigree A. Autosomal recessive, Huntingtin gene Pedigree C, X-linked recessive, Factor VIII gene Pedigree A, Autosomal recessive, HexA geneShown in the pictures below are the degrees of dominance in the inheritance of flower color in some plants. *Based on the phenotypes (or maybe genotype), differentiate between complete dominance, incomplete dominance, and codominance. Be able to discuss the difference briefly but concisely. You may also refer to the definition.Albinism, lack of pigmentation in humans, results from an autosomal recessive gene designated a. Two parents with normal pigmentation have an albino child. What is the probability that their next child will be albino? What is the probability that the next child will be an albino girl? If the child is normal, what is the probability that it will be a carrier (heterozygous) for the albino gene?
- What is the most likely pattern of inheritance for this disorder? (Is it autosomal dominant? Autosomal recessive? X-linked dominant? X-linked recessive? Y-linked? Mitochondrial?) Please include two specific pieces of evidence, present within the pedigree, that indicate that this pattern is most likely, as opposed to any other potential pattern. You may assume that the gene responsible for the trait is fully penetrant.Utilizing the following pedigree, and the key for phenotypes, to the right of it, determine the genotypes of the individuals in the pedigree for blood type inheritance. Individual Blood Type I1 I2 II1 II2 II3 II4 III1 III2 III3 III4 III5 III6One family is shown in both pedigrees below. Each pedigree focuses on a different monogenic, fully penetrant phenotype. Shaded individuals affected by Phenotype 1: 3 Shaded individuals affected by Phenotype 2: a. Phenotype 1: Which modes of inheritance can be ruled out, base don't this pedigree? For each mode of inheritance listed below, either state that it is not ruled out, or describe a detail of the pedigree that allows you to rule it out. Autosomal recessive Autosomal dominant X-linked recessive X-linked dominant Y-linked b. Phenotype 2: Which modes of inheritance can be ruled out, base don't this pedigree? For each mode of inheritance listed below, either state that it is not ruled out, or describe a detail of the pedigree that allows you to rule it out. Autosomal recessive Autosomal dominant X-linked recessive X-linked dominant