The pedigree below shows a family with a history of an autosomal recessive genetic disease with one individual's genotype indicated (G denotes the normal allele and g denotes the disease-causing allele). * 00 O 1/8 O 1/4 Individual 1's father is known to be heterozygous (*) and his mother is known to be homozygous dominant. Other individuals in the pedigree may be carriers, but are not marked. The question mark (?) indicates that you do not yet know anything about this individual's phenotype with regard to the disease. O 1/16 Part 1 What is the probability that individuals 1 and 2 will have a child (5) who is a male with the disease (the child is unborn and the sex is not yet known)? 1/4 1 O 1/6 ? 5 1/8 2 O 1/12 gg 3 Part 2 What is the probability that the daughter (female)(6) that individual 3 and 4 just had will have the disease? 6

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The pedigree below shows a family with a history of an autosomal recessive genetic
disease with one individual's genotype indicated (G denotes the normal allele and g
denotes the disease-causing allele).
*
O 0
O 1/8
1/4
O 1/16
Individual 1's father is known to be heterozygous (*) and his mother is known to be
homozygous dominant. Other individuals in the pedigree may be carriers, but are not
marked. The question mark (?) indicates that you do not yet know anything about this
individual's phenotype with regard to the disease.
Part 1
What is the probability that individuals 1 and 2 will have a child (5) who is a male with the
disease (the child is unborn and the sex is not yet known)?
O 1/4
1
O 1/6
5
1/8
2
01/12
gg
3
Part 2
What is the probability that the daughter (female)(6) that individual 3 and 4 just had will have the
disease?
6
Transcribed Image Text:The pedigree below shows a family with a history of an autosomal recessive genetic disease with one individual's genotype indicated (G denotes the normal allele and g denotes the disease-causing allele). * O 0 O 1/8 1/4 O 1/16 Individual 1's father is known to be heterozygous (*) and his mother is known to be homozygous dominant. Other individuals in the pedigree may be carriers, but are not marked. The question mark (?) indicates that you do not yet know anything about this individual's phenotype with regard to the disease. Part 1 What is the probability that individuals 1 and 2 will have a child (5) who is a male with the disease (the child is unborn and the sex is not yet known)? O 1/4 1 O 1/6 5 1/8 2 01/12 gg 3 Part 2 What is the probability that the daughter (female)(6) that individual 3 and 4 just had will have the disease? 6
Expert Solution
Step 1: Introduction

Pedigree analysis is a family chart used to study the inheritance pattern of traits or diseases within a family and family history. It is a type of family tree that depicts the relationship between family members and their phenotypes (observed traits or diseases). It is easier for geneticists to understand the transmission of genetic traits and identify the patterns of inheritance such as autosomal dominant, autosomal recessive, X-linked etc. 

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