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Once again, justify each answer in one sentence. i) Is gene W most likely a positive or a negative regulator? ii) Is the activity of W activated or inactivated by the presence of fictamine?

Once again, justify each answer in one sentence. i) Is gene W most likely a positive or a negative regulator? ii) Is the activity of W activated or inactivated by the presence of fictamine?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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### Genetic Regulation and Enzyme Activity #### Question 3b: An additional gene, called W, is found that affects the synthesis of enzymes 1 and 2. Mutant d has a recessive mutation in gene W. ### Table: Genotype and Enzyme Activity | strain | genotype | enzyme activity | |------------|----------------------------|----------------------------------| | | W | X | Y | Z | 1 | 2 | 1 | 2 | | | | | | | without fictamine | with fictamine | | wild-type | + | + | + | + | ++ | ++ | -- | -- | | mutant a | + | − | + | + | -- | -- | -- | -- | | mutant b | + | + | − | + | -- | ++ | -- | -- | | mutant c | + | + | + | − | ++ | -- | -- | -- | | mutant d | − | + | + | + | ++ | ++ | ++ | ++ | ### Explanation of the Table **Genotype:** - Columns labeled W, X, Y, and Z represent the presence (+) or absence (−) of specific genes in different strains. **Enzyme Activity:** - Enzyme activity is recorded under conditions without fictamine and with fictamine. - Symbols: - '+' indicates the presence of a gene or enzyme activity. - '−' indicates the absence of a gene or lack of enzyme activity. - '++' indicates higher enzyme activity. - '--' denotes a complete lack of enzyme activity. ### Questions: **i) Is gene W most likely a positive or a negative regulator?** **Answer:** Gene W is most likely a positive regulator because mutant d, which has a recessive mutation in gene W, shows high enzyme activity (++), indicating that the presence of the functional W gene suppresses this activity. **ii) Is the activity of W activated or inactivated by the presence of fictamine?** **Answer:** The activity of W is inactivated by the presence of fictamine, as seen in the wild-type where enzyme activity drops (++) without fictamine to (--) with
Transcribed Image Text:### Genetic Regulation and Enzyme Activity #### Question 3b: An additional gene, called W, is found that affects the synthesis of enzymes 1 and 2. Mutant d has a recessive mutation in gene W. ### Table: Genotype and Enzyme Activity | strain | genotype | enzyme activity | |------------|----------------------------|----------------------------------| | | W | X | Y | Z | 1 | 2 | 1 | 2 | | | | | | | without fictamine | with fictamine | | wild-type | + | + | + | + | ++ | ++ | -- | -- | | mutant a | + | − | + | + | -- | -- | -- | -- | | mutant b | + | + | − | + | -- | ++ | -- | -- | | mutant c | + | + | + | − | ++ | -- | -- | -- | | mutant d | − | + | + | + | ++ | ++ | ++ | ++ | ### Explanation of the Table **Genotype:** - Columns labeled W, X, Y, and Z represent the presence (+) or absence (−) of specific genes in different strains. **Enzyme Activity:** - Enzyme activity is recorded under conditions without fictamine and with fictamine. - Symbols: - '+' indicates the presence of a gene or enzyme activity. - '−' indicates the absence of a gene or lack of enzyme activity. - '++' indicates higher enzyme activity. - '--' denotes a complete lack of enzyme activity. ### Questions: **i) Is gene W most likely a positive or a negative regulator?** **Answer:** Gene W is most likely a positive regulator because mutant d, which has a recessive mutation in gene W, shows high enzyme activity (++), indicating that the presence of the functional W gene suppresses this activity. **ii) Is the activity of W activated or inactivated by the presence of fictamine?** **Answer:** The activity of W is inactivated by the presence of fictamine, as seen in the wild-type where enzyme activity drops (++) without fictamine to (--) with
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