When ligand bin

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Transcribed Text for Educational Website:**

### Questions on Signal Transduction Pathways and Ligand-Receptor Interactions

#### Question 23:
Based on the conserved evolution of signal transduction pathways and the specificity of receptors for ligands, tests were performed that show:

A) Human cells in vitro cultured respond to bovine (cow) hormones  
B) Anural cells can respond to hormones derived from bacteria  
C) Yeast cells use mating type signal to locate mates and respond by making protist cells  
D) Plants hormones have a significant impact on the animals that eat them

#### Question 24:
RAS mutants occur in one-third of all cancers. RAS is a kinase that cross talks with cell growth and apoptosis pathways. When we say RAS mutants are resistant to chemotherapy that means:

A) RAS protein inactivates drugs used in chemotherapy  
B) Drugs that should cause apoptosis fail in mutations in RAS mutant cells  
C) Yeast cells use mating type signal to locate mates and respond by making protist cells  
D) RAS Phosphorylates the drugs used in chemotherapy  

#### Question 25:
When a ligand binds to a ligand gated ion channel receptor, what order of operations occurs?

I. Gate closes  
II. Gate opens  
III. Ions flow through gate  
IV. Ligand is released

Options:  
A) I, II, III, IV  
B) II, III, IV, I  
C) III, II, IV, I  
D) IV, II, III, I  

### Note:
The questions focus on understanding the roles of RAS mutants in cancer and signal transduction pathways involving ligand-gated ion channel receptors.
Transcribed Image Text:**Transcribed Text for Educational Website:** ### Questions on Signal Transduction Pathways and Ligand-Receptor Interactions #### Question 23: Based on the conserved evolution of signal transduction pathways and the specificity of receptors for ligands, tests were performed that show: A) Human cells in vitro cultured respond to bovine (cow) hormones B) Anural cells can respond to hormones derived from bacteria C) Yeast cells use mating type signal to locate mates and respond by making protist cells D) Plants hormones have a significant impact on the animals that eat them #### Question 24: RAS mutants occur in one-third of all cancers. RAS is a kinase that cross talks with cell growth and apoptosis pathways. When we say RAS mutants are resistant to chemotherapy that means: A) RAS protein inactivates drugs used in chemotherapy B) Drugs that should cause apoptosis fail in mutations in RAS mutant cells C) Yeast cells use mating type signal to locate mates and respond by making protist cells D) RAS Phosphorylates the drugs used in chemotherapy #### Question 25: When a ligand binds to a ligand gated ion channel receptor, what order of operations occurs? I. Gate closes II. Gate opens III. Ions flow through gate IV. Ligand is released Options: A) I, II, III, IV B) II, III, IV, I C) III, II, IV, I D) IV, II, III, I ### Note: The questions focus on understanding the roles of RAS mutants in cancer and signal transduction pathways involving ligand-gated ion channel receptors.
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