n case of the same amino acid as in the picture, in which ionization state would this amino acid be at (i) a pH that will correspond with the pI-value and (ii) a pH below the pI-value?

Q: Why is the ionic bond between, say, the side chain of lysine and the side chain of glutamic acid…

A: Amino acids are the molecules that join to form a protein structure. The bond formed between two…

Q: Suggest a reason why amino acids are usually more soluble at pH extremes than they are at neutral…

A: Introduction: Amino acids are a group of organic compounds containing two functional groups- amino…

Q: Chymotrypsin is a pH dependent protein. Enzymatic activity is the greatest between pH=7.0 to pH=8.5.…

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Q: Draw Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly peptide. What is the net charge of this peptide at pH 3, 8…

A: polypeptides are made up of amino acids that are joined together by peptide bonds (covalent in…

Q: Consider the peptides Pro-Gin-Val-Phe-His-Asp-Cys and His-Gln-Pro-Cys-Asp-Phe-Val. How do these two…

A: Amino acids are biomolecules in which an amino group and a carboxyl group are linked to the same…

Q: 6. Would Lys-Glu-Ser have the same pl as Ser-Glu-Lys? Explain.

A: Note: The given picture contains multiple questions and as per the guidelines we'll answer the first…

Q: Using the data in Table calculate the average amino acid residue weight in a protein of typical…

A: Amino acids are the compounds that acts as the building block of proteins. Each amino acids are…

Q: The dissociation constant, Kd for a complex between protein A and protein B is 4.1 μM. If the two…

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Q: What is the optimum pH to separate a mixture of lysine, arginine, andcysteine using electrophoresis?…

A: Electrophoresis is the technique used for the separation of proteins based on the charge and size of…

Q: What determines when an amino acid ionized? i.e. Why are both Lysine (pKa 10.53) and Argenine (pKa…

A: Amino acid are the building blocks of the protein. Each amino acid has a common basic structure with…

Q: The following amino acid is dissolved in solution at pH 7.4. HC H + CH CH₂ H H+ HC a. Which amino…

A: Dissociation of a weak acid is mathematically described by the Henderson-Hasselbalch equation:pH =…

Q: 13.4) In the previous problem, you drew the predominant form of leucine at pH= 1.0, pH = 7.4, and pH…

A: Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon…

Q: Give the general Adiar equation for the binding of a ligand to a dimeric protein. Explain further…

A: Cooperativity- It is a character of some multi-subunit enzymes, where different subunits has…

Q: Consider a peptide with the sequence Ala-Glu-Arg-Leu. Assume the ionizable groups have the pKa…

A: Amino acid sequences are written with N-terminal amino acid on the left and C-terminal amino acid on…

Q: What is the Isoelectric point of Y-R-S (pH 7-11)  What is the isoelectric point of N-G-L (pH 1-5)

A: Isoelectric point (PI) is the pH at which the molecule has no net electrical charge. Each amino acid…

Q: whereas protein B does not absorb at 340 nm. What absorbance will be observed when light at 340 nm…

A: Given, ε (extinction coefficient) = 6440 M-1 cm-1 l (path length) = 5 mm = 0.5 cm c (concentration)…

Q: Suppose you have a mixture of the following proteins protein A: pl = 3.5, mw = 35 kDa protein B: pl…

A: Cation exchange chromatography is defined as part of the ion-exchange chromatography. It is used to…

Q: Assume that some protein molecule, in its folded native state, has one favored conformation. But…

A: "Protein Folding" primarily concerns the comprehensive physical process of transformation from…

Q: The melanocyte-stimulating peptide hormone α-melanotropin has the following sequence:…

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Q: On the paper provided, draw the chemical structure of a peptide with a sequence LEMD at pH 7. The…

A: Here, we are given the peptide LEMD. There are 4 ionizable groups in the peptide. They…

Q: Sketch the following two tripeptide chains: Asp-Gly-Ser and Ile-Asn-Met at physiological pH .…

A: Peptide are composed of 5-10 amino acids linked by peptide/amide bonds. Alpha carbon of amino acids…

Q: One liter of a 0.1 M Tris buffer (pKa of Tris = 8.3, see Table 2.4) is prepared and adjusted to a pH…

A: Given Values: pKa of tris = 8.3 pH of the buffer = 2.0

Q: At pH = 7.0 the degree of %3D protonation of histidine side chain (pKa = 6.5) will be. %3D

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Q: The molecular iodine (12) in betadine is susceptible to decomposition if exposed to direct sunlight,…

A: Redox titration using iodine is used to calculate the amount of Ascorbic acid in any sample. Vitamin…

Q: An oligopeptide has the following amino acid sequence:…

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Q: Do you predict that this salt bridge will become stronger, become weaker, or be unaffected as pH…

A: Salt bridges are attractive interactions between two oppositely charged groups. So, more oppositely…

Q: It is well known that sphingomyelin interacts with cholesterol and high affinity. What do you…

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Q: Please select the answer that would complete the following statement corretly. The charge of acetic…

A: The charge on the acetic acid (CH₃COOH) is due to the carboxylic acid functional group. It is a weak…

Q: Given the following pKa data for the individual amino acids, estimate the pI for the tripeptide…

A: In the given data pKa  of amino acids Thr-Asp-Arg is: Thr-? Asp-3.86 Arg-12.48 N-terminal group-…

Q: Polymer beads (resin) made of DEAE (diethylaminoethyl) cellulose are packed in an ion exchange…

A: DEAE cellulose resin had some  groups which are positively charged and can bind proteins through…

Q: Amino acid structure For any ionizable group, indicate the pka value and draw the structure that…

A: All ionizable groups have their characteristic pKa value. pKa is the pH at which half of all the…

Q: Consider a protein in which a negatively charged glutamic acid side chain (pKa = 4.2) makes a salt…

A: Salt bridges are attractive interactions between two oppositely charged groups. So, more oppositely…