Multiple Alleles 12. The major blood groups in humans are determined by multiple alleles; that is there are more than two possible alleles, any one of which can occupy a locus. In this ABO blood group system, a single gene can exist in any of three aillelic forms: I^, ", or i. The alleles A and B code for production of antigen A and antigen B (two proteins) on the surface of red blood cells. Alleles A and B are codominant, while allele i is recessive. Four blood groups (phenotypes) are possible from combinations of these alleles (Table 1). TABLE 1 The ABO Blood Groups Blood Type Anitgens Present Antibody Present Genotype Neither A nor B A and B A A B A AB AB Neither A nor B a. Is it possible for a child with blood type O to be produced by two AB parents? - Explain - (yes or no) b. In a case of disputed paternity, the child is type O, the mother type A. Could an individual of the following blood types be the father?. - Ēxplain each possibility. A В AB
Multiple Alleles 12. The major blood groups in humans are determined by multiple alleles; that is there are more than two possible alleles, any one of which can occupy a locus. In this ABO blood group system, a single gene can exist in any of three aillelic forms: I^, ", or i. The alleles A and B code for production of antigen A and antigen B (two proteins) on the surface of red blood cells. Alleles A and B are codominant, while allele i is recessive. Four blood groups (phenotypes) are possible from combinations of these alleles (Table 1). TABLE 1 The ABO Blood Groups Blood Type Anitgens Present Antibody Present Genotype Neither A nor B A and B A A B A AB AB Neither A nor B a. Is it possible for a child with blood type O to be produced by two AB parents? - Explain - (yes or no) b. In a case of disputed paternity, the child is type O, the mother type A. Could an individual of the following blood types be the father?. - Ēxplain each possibility. A В AB
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Transcribed Image Text:Multiple Alleles
12. The major blood groups in humans are determined by multiple alleles; that is there are more than two
possible alleles, any one of which can occupy a locus.
In this ABO blood group system, a single gene can exist in any of three allelic forms: 14, #, or i. The
alleles A and B code for production of antigen A and antigen B (two proteins) on the surface of red blood
cells. Alleles A and B are codominant, while allele i is recessive.
Four blood groups (phenotypes) are possible from combinations of these alleles (Table 1).
TABLE 1 The ABO Blood Groups
Blood Type
Anitgens Present
Antibody Present
Genotype
Neither A nor B
A and B
A
A
B
MA or Ai
B
B
A
АВ
АВ
Neither A nor B
a. Is it possible for a child with blood type O to be produced by two AB parents?
Explain
- (yes or no)
b. In a case of disputed paternity, the child is type O, the mother type A. Could an individual of the
following blood types be the father?
Explain each possibility.
A.
В
АВ
Expert Solution
Step 1
Blood type of the human is governed by multiple alleles and a single gene can exist in three allelic forms: a gene for blood group exist in IA, IB and i.
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