Whitt noted leukocoria and strabismus. Define these terms. Based on what you know so far, create a pedigree that depicts the prevalence of cancer in this family. Indicate Kay as the proband. Consider the pedigree that you just drew. What mode of inheritance seems most likely? Justify your prediction.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 7QP
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  1. Whitt noted leukocoria and strabismus. Define these terms.
  2. Based on what you know so far, create a pedigree that depicts the prevalence of cancer in this family. Indicate Kay as the proband.
  3. Consider the pedigree that you just drew. What mode of inheritance seems most likely? Justify your prediction.
  4. What is the difference between a sporadic cancer and an inherited (or familial) cancer? Which is most common?
  5. Based on the pedigree you drew; do you think that the cancer in this family tree is sporadic or inherited? Why?
  6. Briefly, describe the fundamental problem that distinguishes a cancer cell from a non-cancerous cell.
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