5. Hemophilia is caused by an X-linked recessive mutation in humans. If a woman whose paternal uncle (father's brother) was a hemophiliac marries a man whose brother is also a hemophiliac, what is the probability that their first child will have hemophilia? (Assume that no other cases of hemophilia and no hidden carriers exist in the family.) Draw the pedigree of the known people in the families along with the genotypes to show how you are able to calculate the probability.
5. Hemophilia is caused by an X-linked recessive mutation in humans. If a woman whose paternal uncle (father's brother) was a hemophiliac marries a man whose brother is also a hemophiliac, what is the probability that their first child will have hemophilia? (Assume that no other cases of hemophilia and no hidden carriers exist in the family.) Draw the pedigree of the known people in the families along with the genotypes to show how you are able to calculate the probability.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Need help on #5 of my genetic questions

Transcribed Image Text:5. Hemophilia is caused by an X-linked recessive mutation in humans. If a woman whose paternal
uncle (father's brother) was a hemophiliac marries a man whose brother is also a hemophiliac,
what is the probability that their first child will have hemophilia? (Assume that no other cases of
hemophilia and no hidden carriers exist in the family.) Draw the pedigree of the known people in
the families along with the genotypes to show how you are able to calculate the probability.
Expert Solution

Step 1
In the disease called “haemophilia”, if a wound is created, the blood does not clot normally. This occurs because the person who suffers from haemophilia lacks sufficient blood clotting factors in his body. This is an inherited disease by which males are affected. Women may be carriers of haemophilia. Among the sex chromosomes, haemophilia is carried by the X chromosome.
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