Match each of the changes that can contribute to cancer with its correct description. Loss of function of regulators that send old or damaged cells into apoptosis Hyperactivation of signalling pathways that tell the cell to grow and divide 1. Sustaining proliferative signalling Loss of function of structural proteins that anchor cells to surrounding tissue and/or activation of cell migration 2. Evading growth suppressors 3. Activating invasion and metastasis Loss of function of 4. Enabling replicative immortality regulators that stop inappropriate growth and cell division 5. Inducing angiogenesis 6. Resisting cell death Loss of function of regulators that force aging cells to exit the cell cycle and enter GO or replicative senescence

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Match each of the changes that can contribute to cancer with its correct description.
Loss of function of
regulators that send old or
damaged cells into
apoptosis
Hyperactivation of
signalling pathways that tell
the cell to grow and divide
1. Sustaining proliferative signalling
Loss of function of
structural proteins that
anchor cells to surrounding
tissue and/or activation of
cell migration
2. Evading growth suppressors
3. Activating invasion and metastasis
Loss of function of
4. Enabling replicative immortality
regulators that stop
inappropriate growth and
cell division
5. Inducing angiogenesis
6. Resisting cell death
Loss of function of
regulators that force aging
cells to exit the cell cycle
and enter GO or replicative
senescence
00
Transcribed Image Text:Match each of the changes that can contribute to cancer with its correct description. Loss of function of regulators that send old or damaged cells into apoptosis Hyperactivation of signalling pathways that tell the cell to grow and divide 1. Sustaining proliferative signalling Loss of function of structural proteins that anchor cells to surrounding tissue and/or activation of cell migration 2. Evading growth suppressors 3. Activating invasion and metastasis Loss of function of 4. Enabling replicative immortality regulators that stop inappropriate growth and cell division 5. Inducing angiogenesis 6. Resisting cell death Loss of function of regulators that force aging cells to exit the cell cycle and enter GO or replicative senescence 00
Hyperactivation of
signalling pathways that tell
the cell to grow and divide
1. Sustaining proliferative signalling
Loss of function of
structural proteins that
anchor cells to surrounding
tissue and/or activation of
cell migration
2. Evading growth suppressors
3. Activating invasion and metastasis
Loss of function of
4. Enabling replicative immortality
regulators that stop
inappropriate growth and
cell division
5. Inducing angiogenesis
Loss of function of
6. Resisting cell death
regulators that force aging
cells to exit the cell cycle
and enter GO or replicative
senescence
Activation of genes that
promote growth of new
blood vessels
Transcribed Image Text:Hyperactivation of signalling pathways that tell the cell to grow and divide 1. Sustaining proliferative signalling Loss of function of structural proteins that anchor cells to surrounding tissue and/or activation of cell migration 2. Evading growth suppressors 3. Activating invasion and metastasis Loss of function of 4. Enabling replicative immortality regulators that stop inappropriate growth and cell division 5. Inducing angiogenesis Loss of function of 6. Resisting cell death regulators that force aging cells to exit the cell cycle and enter GO or replicative senescence Activation of genes that promote growth of new blood vessels
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