Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations.The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene?Inhibit cell growth and divisionOncogeneInhibit apoptosisMetabolic enzymeEXPLAIN in 1-2 sentences:A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation?an activating mutation in a tumor suppressor genean activating mutation in a proto-oncogenea loss of function mutation in a tumor suppressor genea loss of function mutation in a proto-oncogeneEXPLAIN in 1-2 sentences:In an otherwise normal cell, what would be the immediate result of a proto-oncogene mutating into an oncogene?apoptosisnot much; perhaps a slight quickening of the cell cyclethe cell would become malignantrapid mutations of other genesEXPLAIN in 1-2 sentences:

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Answered: The ABC gene undergoes multiple gene…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations.

The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene?
Inhibit cell growth and division
Oncogene
Inhibit apoptosis
Metabolic enzyme

EXPLAIN in 1-2 sentences:

A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation?
an activating mutation in a tumor suppressor gene
an activating mutation in a proto-oncogene
a loss of function mutation in a tumor suppressor gene
a loss of function mutation in a proto-oncogene

EXPLAIN in 1-2 sentences:

In an otherwise normal cell, what would be the immediate result of a proto-oncogene mutating into an oncogene?
apoptosis
not much; perhaps a slight quickening of the cell cycle
the cell would become malignant
rapid mutations of other genes

EXPLAIN in 1-2 sentences:

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