Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations.The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene?Inhibit cell growth and divisionOncogeneInhibit apoptosisMetabolic enzymeEXPLAIN in 1-2 sentences:A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation?an activating mutation in a tumor suppressor genean activating mutation in a proto-oncogenea loss of function mutation in a tumor suppressor genea loss of function mutation in a proto-oncogeneEXPLAIN in 1-2 sentences:In an otherwise normal cell, what would be the immediate result of a proto-oncogene mutating into an oncogene?apoptosisnot much; perhaps a slight quickening of the cell cyclethe cell would become malignantrapid mutations of other genesEXPLAIN in 1-2 sentences:

(Note: Kindly note that, since you have added multiple questions, we are only able to answer one question at a time, please paste other questions separately.) Question 1: The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene? Cancer is a genetic disease. It is not a single disease rather; it is two or more hundreds of diseases. It almost affects all organ systems, tissues, and cells. The growth of the cells is uncontrolled, and the cells are abnormal which leads to cancer. There are over two hundred types of cancer known. The causative agents to cause cancer are –chemicals, ionization radiation, pathogens, human genetics, compound exposure, poor lifestyle, diet, environmental factors, etc.Justification for correct answer: Option 2: Oncogenes the correct choice of answer, because ABC is the gene which undergoes multiple gene duplication events, and this gene duplication event associated with cancer. Oncogenes are the genes responsible for the division of cells and if duplication of ABC genes leads to cancer, then ABC should be Oncogenes. Justification for the incorrect answer: Option 1: Inhibit cell growth division, this option is not correct because if the ABC gene is associated with the Inhibition of the cell growth division, then duplication of the ABC, a gene should not cause cell division, hence this option is not correct. Option 3: Inhibit apoptosis, apoptosis is the programmed cell death, if the ABC gene is the gene which inhibits apoptosis then duplication of this gene, should not cause cancer, hence this option is also not correct. Option 4: Metabolic enzymes, metabolic enzymes do not have any relation with cancer development, hence the ABC gene should not be the genes of the metabolic enzymes.

Answered: The ABC gene undergoes multiple gene…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations.

The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene?
Inhibit cell growth and division
Oncogene
Inhibit apoptosis
Metabolic enzyme

EXPLAIN in 1-2 sentences:

A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation?
an activating mutation in a tumor suppressor gene
an activating mutation in a proto-oncogene
a loss of function mutation in a tumor suppressor gene
a loss of function mutation in a proto-oncogene

EXPLAIN in 1-2 sentences:

In an otherwise normal cell, what would be the immediate result of a proto-oncogene mutating into an oncogene?
apoptosis
not much; perhaps a slight quickening of the cell cycle
the cell would become malignant
rapid mutations of other genes

EXPLAIN in 1-2 sentences:

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