Answer with explanation please 5.You are a researcher working on a treatment for Hutchinson-Gilford progeria syndrome, an extremely raregenetic disorder that causes accelerated aging in children. Children with progeria generally appear healthyat birth but soon start growing more slowly than other children and lose their hair. Additional symptomsinclude stiffness of joints, heart problems, and stroke. These children typically die of heart disease at anaverage age of 13 years.Progeria is caused by a mutation in a single gene, called lamin A. Scientists have identified over 1,400mutations in the lamin A gene that result in changes in transcription, RNA splicing, and/or proteinproduction. Lamin A codes for a protein required for the structural support of the nuclear envelope in cells.Without a functional protein, the nuclear envelope becomes unstable, eventually damaging the nucleus andcausing cells to die.Based on what you learned in this Click & Learn, propose a genetic medicine strategy you could develop totreat patients with progeria. Describe which step in gene expression you might target and why you wouldtarget that step, the intervention tool you would use, and explain how this strategy would treat the disease.

Name: Answer with explanation please 5.You are a researcher working on a tre
Uploaded: 2024-03-20T06:42:55.000Z
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Description: Answer with explanation please 5.You are a researcher working on a treatment for Hutchinson-Gilford progeria syndrome, an extremely raregenetic disorder that causes accelerated aging in children. Children with progeria generally appear healthyat birt