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1. Based on their descriptions, classify each gene as a tumor suppressor or a proto- oncogene: Tumor suppressor or| proto-oncogene? Gene Protein product activity A transcription factor that turns many genes on or off. Normally, p53 is produced at high levels only when DNA damage is detected. Controls the G1/S cell cycle checkpoint. When it's present, it makes sure E2F is neutralized until it's time to proceed with DNA synthesis. A transcription factor that turns on genes needed for cell cycle progression. Binds and destroys TCF before it can enter the p53 RB1 Мус АРС nucleus. TCF A transcription factor that turns on the Myc gene. 2. Choose one of the genes from the above table and do some research. Which cancers usually have mutations in this gene?

1. Based on their descriptions, classify each gene as a tumor suppressor or a proto- oncogene: Tumor suppressor or| proto-oncogene? Gene Protein product activity A transcription factor that turns many genes on or off. Normally, p53 is produced at high levels only when DNA damage is detected. Controls the G1/S cell cycle checkpoint. When it's present, it makes sure E2F is neutralized until it's time to proceed with DNA synthesis. A transcription factor that turns on genes needed for cell cycle progression. Binds and destroys TCF before it can enter the p53 RB1 Мус АРС nucleus. TCF A transcription factor that turns on the Myc gene. 2. Choose one of the genes from the above table and do some research. Which cancers usually have mutations in this gene?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1. Based on their descriptions, classify each gene as a tumor suppressor or a proto- oncogene: Tumor suppressor or proto-oncogene? Gene Protein product activity A transcription factor that turns many genes on or off. Normally, p53 is produced at high levels only when DNA damage is detected. Controls the G1/S cell cycle checkpoint. When it's present, it makes sure E2F is neutralized until it's time to proceed with DNA synthesis. A transcription factor that turns on genes needed for cell cycle progression. Binds and destroys TCF before it can enter the nucleus. р53 RB1 Мус АРС TCF A transcription factor that turns on the Myc gene. 2. Choose one of the genes from the above table and do some research. Which cancers usually have mutations in this gene?
Transcribed Image Text:1. Based on their descriptions, classify each gene as a tumor suppressor or a proto- oncogene: Tumor suppressor or proto-oncogene? Gene Protein product activity A transcription factor that turns many genes on or off. Normally, p53 is produced at high levels only when DNA damage is detected. Controls the G1/S cell cycle checkpoint. When it's present, it makes sure E2F is neutralized until it's time to proceed with DNA synthesis. A transcription factor that turns on genes needed for cell cycle progression. Binds and destroys TCF before it can enter the nucleus. р53 RB1 Мус АРС TCF A transcription factor that turns on the Myc gene. 2. Choose one of the genes from the above table and do some research. Which cancers usually have mutations in this gene?
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