Imagine a protein that normally functions in the nucleus. If you added an ER signal sequence to the N-terminal end of the gene that expresses this nuclear protein (through genetic manipulation), what would be the fate of the expressed protein? The protein would reside in the cytoplasm. The protein would reside in the cell membrane. The protein would reside in the ER. The protein would reside in the nucleus.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Imagine a protein that normally functions in the nucleus.
If you added an ER signal sequence to the N-terminal end of the gene that expresses
this nuclear protein (through genetic manipulation), what would be the fate of the
expressed protein?
The protein would reside in the cytoplasm.
The protein would reside in the cell membrane.
The protein would reside in the ER.
The protein would reside in the nucleus.
Transcribed Image Text:Imagine a protein that normally functions in the nucleus. If you added an ER signal sequence to the N-terminal end of the gene that expresses this nuclear protein (through genetic manipulation), what would be the fate of the expressed protein? The protein would reside in the cytoplasm. The protein would reside in the cell membrane. The protein would reside in the ER. The protein would reside in the nucleus.
Expert Solution
Step 1

The translation of proteins occurs by membrane free ribosomes or by membrane bound ribosomes. The decision of translation by which type of ribosomes depends on the specific sequence present in the polypeptide chain.

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