If an isolated liver cell runs out of glucose, the cell will break down glycogen into Glucose-1-Phosphate (Glucose-1-P). The isolated liver cell will then use the enzyme phosphoglucomutase to convert Glucose-1-P to Glucose-6-P, which can enter glycolysis. If you remove all glucose and add a drug that inhibits phosphoglucomutase, which molecule will most likely accumulate in this system?    A. Glucose B. Glucose 1 phosphate C. Glucose 6 phosphate D. Lactate E. CO2

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You have the following pathway: 

 If an isolated liver cell runs out of glucose, the cell will break down glycogen into Glucose-1-Phosphate (Glucose-1-P).  The isolated liver cell will then use the enzyme phosphoglucomutase to convert Glucose-1-P to Glucose-6-P, which can enter glycolysis.  If you remove all glucose and add a drug that inhibits phosphoglucomutase, which molecule will most likely accumulate in this system? 

 

A. Glucose
B. Glucose 1 phosphate
C. Glucose 6 phosphate
D. Lactate
E. CO2
GLYCOGEN
PHOSPHORYLASE
Glycogen
Glucose-1-P
PHOSPHOGLUCOMUTASE
Glucose-6-P
GLYCOLYSIS
Pyruvate
PYRUVATE
DEHYDROGENASE
Acetyl COA
GLUCOSE-6-PHOSPHATASE
(liver and kidney only)
LACTATE DEHYDROGENASE
00₂
Glucose
Lactate
Transcribed Image Text:GLYCOGEN PHOSPHORYLASE Glycogen Glucose-1-P PHOSPHOGLUCOMUTASE Glucose-6-P GLYCOLYSIS Pyruvate PYRUVATE DEHYDROGENASE Acetyl COA GLUCOSE-6-PHOSPHATASE (liver and kidney only) LACTATE DEHYDROGENASE 00₂ Glucose Lactate
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