ic Asian avian flu causes a fatal infection in about 60% of t

Human Anatomy & Physiology (11th Edition)
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The highly pathogenic Asian avian flu causes a fatal infection in about 60% of the individuals infected. The seasonal flu vaccine does not provide protection against this strain of Influenza. Is the highly pathogenic Asian avian flu likely to be an H1N1 or H3N2 strain of influenza? Why or why not?

**Influenza Virus Structures: H1N1 and H3N2**

This section provides a detailed visual explanation of the structural differences between two influenza virus subtypes: H1N1 and H3N2.

**Diagram Breakdown:**

1. **H1N1:**
    - **Structure Description:** The schematic on the left represents the H1N1 influenza virus.
    - **Outer Proteins:** Two types of surface proteins are shown, labeled as "H" and "N". 
        - "H" (Hemagglutinin) proteins are depicted in red and are rod-shaped.
        - "N" (Neuraminidase) proteins are depicted in blue and are club-shaped.
    - **Core Components:** Inside the virus are depicted various "nucleoproteins," which are involved in housing the virus's RNA genetic material. These are shown as strands inside the virus particle.
    
2. **H3N2:**
    - **Structure Description:** The schematic on the right represents the H3N2 influenza virus.
    - **Outer Proteins:** Similar to H1N1, but with different surface proteins, labeled as "H" and "N".
        - "H" (Hemagglutinin) proteins are depicted in green and are rod-shaped.
        - "N" (Neuraminidase) proteins are depicted in orange and are club-shaped.
    - **Core Components:** Inside the virus are also nucleoproteins, which protect the virus’s RNA genetic material.

**Key Points:**

1. **Hemagglutinin (H) Proteins:** The primary role of hemagglutinin is to bind to the host cell receptors, allowing the virus to enter the cell.
2. **Neuraminidase (N) Proteins:** Neuraminidase helps the virus to release newly formed viral particles from the host cell, facilitating the spread of infection.
3. **Nucleoproteins:** They are critical for the replication and transcription of the viral RNA, shielding the genetic material of the virus.

Understanding the structure of these viruses helps in devising vaccines and treatments, as it identifies targets for antibodies and antiviral drugs to inhibit the virus' function.
Transcribed Image Text:**Influenza Virus Structures: H1N1 and H3N2** This section provides a detailed visual explanation of the structural differences between two influenza virus subtypes: H1N1 and H3N2. **Diagram Breakdown:** 1. **H1N1:** - **Structure Description:** The schematic on the left represents the H1N1 influenza virus. - **Outer Proteins:** Two types of surface proteins are shown, labeled as "H" and "N". - "H" (Hemagglutinin) proteins are depicted in red and are rod-shaped. - "N" (Neuraminidase) proteins are depicted in blue and are club-shaped. - **Core Components:** Inside the virus are depicted various "nucleoproteins," which are involved in housing the virus's RNA genetic material. These are shown as strands inside the virus particle. 2. **H3N2:** - **Structure Description:** The schematic on the right represents the H3N2 influenza virus. - **Outer Proteins:** Similar to H1N1, but with different surface proteins, labeled as "H" and "N". - "H" (Hemagglutinin) proteins are depicted in green and are rod-shaped. - "N" (Neuraminidase) proteins are depicted in orange and are club-shaped. - **Core Components:** Inside the virus are also nucleoproteins, which protect the virus’s RNA genetic material. **Key Points:** 1. **Hemagglutinin (H) Proteins:** The primary role of hemagglutinin is to bind to the host cell receptors, allowing the virus to enter the cell. 2. **Neuraminidase (N) Proteins:** Neuraminidase helps the virus to release newly formed viral particles from the host cell, facilitating the spread of infection. 3. **Nucleoproteins:** They are critical for the replication and transcription of the viral RNA, shielding the genetic material of the virus. Understanding the structure of these viruses helps in devising vaccines and treatments, as it identifies targets for antibodies and antiviral drugs to inhibit the virus' function.
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