How to draw titration of amino acids ?what happen when ph increase from low to high? 1. what does it means when pka and ph are equal? 2. Did I calculate p1 correctly?? 3. Does cysteine lose H in SH ?should it be positively charged or negatively charged after lose H and why??
How to draw titration of amino acids ?what happen when ph increase from low to high? 1. what does it means when pka and ph are equal? 2. Did I calculate p1 correctly?? 3. Does cysteine lose H in SH ?should it be positively charged or negatively charged after lose H and why??
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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How to draw titration of amino acids ?what happen when ph increase from low to high?
1. what does it means when pka and ph are equal?
2. Did I calculate p1 correctly??
3. Does cysteine lose H in SH ?should it be positively charged or negatively charged after lose H and why??
Expert Solution
Amino acids can act like an weak acid or base
Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon called alpha carbon. Other than the amino and carboxyl groups, amino acids have a side chain linked to the alpha carbon. Amino acids differ from each other in the side group that is linked to the alpha carbon.
The alpha-amino group and alpha-carboxyl groups are ionisable, the side group is ionisable in only some amino acids. When amino acids are dissolved in water, they can act either like an acid or like a base. This is why they are called dipolar ions or zwitterion.
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