The activity of pepsin was measured at various pH values. The temperature and the concentrations of pepsin and substrate were held constant. The following activities were obtained:pH activity1.0 0.51.5 2.62.0 4.83.0 2.04.0 0.45.0 0.0 Plot a graph of the pH dependence of pepsin activity. Based on the graph what is the optimum pH? Predict the activity of pepsin in the blood at pH 7.4.

Pepsin is a protein digestive enzyme, which is known to digest protein into simple and degraded…

Answered: The activity of pepsin was measured at…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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The activity of pepsin was measured at various pH values. The temperature and the concentrations of pepsin and substrate were held constant. The following activities were obtained:

pH activity

1.0 0.5

1.5 2.6

2.0 4.8

3.0 2.0

4.0 0.4

5.0 0.0

Plot a graph of the pH dependence of pepsin activity.
Based on the graph what is the optimum pH?
Predict the activity of pepsin in the blood at pH 7.4.

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