Histidine is an amino acid with three ionizable groups, one of which has a pKa of 6.0. This group, when protonated, has a positive charge. If this ionizable group, within a protein, forms an ionic interaction with a negatively charged group, what would you predict would happen to the pKa of the histidine ionizable group? A. Increase B. Decrease C. Stay the same

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Osmosis

In simple words, osmosis is the slow, gradual movement of a liquid through a membrane. But there are nuances to this process. For instance, there has to be an imbalance in the distribution of solute in the liquid on either side of the membrane, which has to be semipermeable. The liquid in the region with a lower solute concentration moves to the region with a higher concentration, thereby displacing the solution in the process. The objective is to equalize the concentration of molecules on both sides of the membrane; the displacement of liquid can be viewed as a byproduct of this equalization. Since there is no energy required to carry osmosis, it is considered a passive process.