+H₂N-CH-COO™ I CH₂ 1 CH₂ 1 CH₂ I +H₂N-CH₂ A. O amino acid C O amino acid D O amino acid E amino acid B +H₂N-CH-COO™ O amino acid A B. If the pH decreases enough, this amino acid will become protonated and could contribute to the denaturation of the protein. +H₂N-CH-COO™ 1 CH₂ I OH C. +H₂N-CH-COO™ CH H₂C CH3 D.

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**Transcription for Educational Website:**

This image presents a multiple-choice question on amino acids related to their protonation at decreasing pH levels.

**Amino Acid Structures:**

- **A.**
  - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\)
  - R-group: Side chain with \(\text{CH}_2\), \(\text{CH}_2\), \(\text{CH}_2\), \(\text{CH}_2\), \(^+\text{H}_3\text{N} - \text{CH}_2\)

- **B.**
  - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\)
  - R-group: Side chain with \(\text{CH}_2\), \(\text{CH}_2\), \(\text{COO}^-\) 

- **C.**
  - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\)
  - R-group: Side chain with \(\text{CH}_2\), \(\text{OH}\)

- **D.**
  - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\)
  - R-group: Side chain with \(\text{H}_3\text{C - C}\text{H}_3\)

**Question:**

"If the pH decreases enough, this amino acid will become protonated and could contribute to the denaturation of the protein."

**Answer Options:**

- ⃝ amino acid C
- ⃝ amino acid D
- ⃝ amino acid E
- ⦿ amino acid B (correct answer)
- ⃝ amino acid A

**Explanation:**

When the pH of a solution decreases, it becomes more acidic, leading amino acids with acidic side chains, like the one in option B (\(\text{COO}^-\)), to accept protons (\(\text{H}^+\)) and become protonated.

This protonation can potentially disrupt intramolecular interactions, leading to the denaturation of proteins.
Transcribed Image Text:**Transcription for Educational Website:** This image presents a multiple-choice question on amino acids related to their protonation at decreasing pH levels. **Amino Acid Structures:** - **A.** - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\) - R-group: Side chain with \(\text{CH}_2\), \(\text{CH}_2\), \(\text{CH}_2\), \(\text{CH}_2\), \(^+\text{H}_3\text{N} - \text{CH}_2\) - **B.** - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\) - R-group: Side chain with \(\text{CH}_2\), \(\text{CH}_2\), \(\text{COO}^-\) - **C.** - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\) - R-group: Side chain with \(\text{CH}_2\), \(\text{OH}\) - **D.** - Structure: \(^+\text{H}_3\text{N} - \text{CH} - \text{COO}^-\) - R-group: Side chain with \(\text{H}_3\text{C - C}\text{H}_3\) **Question:** "If the pH decreases enough, this amino acid will become protonated and could contribute to the denaturation of the protein." **Answer Options:** - ⃝ amino acid C - ⃝ amino acid D - ⃝ amino acid E - ⦿ amino acid B (correct answer) - ⃝ amino acid A **Explanation:** When the pH of a solution decreases, it becomes more acidic, leading amino acids with acidic side chains, like the one in option B (\(\text{COO}^-\)), to accept protons (\(\text{H}^+\)) and become protonated. This protonation can potentially disrupt intramolecular interactions, leading to the denaturation of proteins.
Expert Solution
Step 1: Introduce amino acid

The structural unit of proteins,  that is made up of carbon, hydrogen oxygen and nitrogen are called amino acid. 

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