A. What change should disrupt the interaction between proteins 1 and 2 the most? Why? B. What change would disrupt the interaction between proteins 1 and 2 the least? Why?
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
A. What change should disrupt the interaction between proteins 1 and 2 the most? Why?
B. What change would disrupt the interaction between proteins 1 and 2 the least? Why?
Introduction:
Proteins are the polymers of Proteins plays an important role in the formation and function of cells.
Example: DNA ligase
Explanation:
The side chain of arginine protein 1 has a positive charge while the side chain of amino acid glutamic acid side chain of protein 2 has a negative charge.
The most probable interaction between these two amino acids is an ionic bond, for example an attractive power between the positive and negative charge.
A.
When the amino acid of protein 2 were mutated to an amino acid with a positive charge. For example, lysine, at that point the positive charges of the arginine of protein 1 and the lysine of protein 2 would repulse one another. Lysine would be the most disrupted to protein-protein interaction.
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