The structures of the amino acids lysine and aspartic acid are shown: H CH₂ OH НО NH, Lysine Aspartic Acid The tertiary structure of a given protein contains an interaction between aspartic acid and lysine. a. Explain how the structure of amino acids determine the function.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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The structures of the amino acids lysine and aspartic acid are shown:
H₂
H
OH
CH₂
CH₂
CH₂
CH₂
NH₂
Lysine
H
H
H
N-C-C
CH₂
C
OH
O
НО
Aspartic Acid
The tertiary structure of a given protein contains an interaction between aspartic acid and lysine.
a. Explain how the structure of amino acids determine the function.
b. A mutation occurred in DNA of a globular enzyme. If the lysine amino acids were found within the active site of the enzyme, describe the effect this change is likely to have on enzymatic function.
c. If a mutation in the DNA of a globular enzyme changed all of the lysine amino acids to aspartic acid, predict how the relative position of the amino acid in the tertiary structure of the protein would be affected when
the protein is placed in an aqueous solution.
d. Justify your prediction by providing evidence that supports your claim.
Transcribed Image Text:The structures of the amino acids lysine and aspartic acid are shown: H₂ H OH CH₂ CH₂ CH₂ CH₂ NH₂ Lysine H H H N-C-C CH₂ C OH O НО Aspartic Acid The tertiary structure of a given protein contains an interaction between aspartic acid and lysine. a. Explain how the structure of amino acids determine the function. b. A mutation occurred in DNA of a globular enzyme. If the lysine amino acids were found within the active site of the enzyme, describe the effect this change is likely to have on enzymatic function. c. If a mutation in the DNA of a globular enzyme changed all of the lysine amino acids to aspartic acid, predict how the relative position of the amino acid in the tertiary structure of the protein would be affected when the protein is placed in an aqueous solution. d. Justify your prediction by providing evidence that supports your claim.
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