Helen has prepared 1000 mL of an IV infusion solution that contains a number of components such as electrolytes, a medication, and a buffering agent to ensure a pH close to that of blood. This preparation has an osmolality of 600 mOsmol/kg. Note that preparations that are isotonic have an osmolality close to that of blood (i.e., 285–295 mOsm/kg). 1, What is the tonicity nature of this solution? Why? Isotonic Hypertonic Hypotonic (Napra 3.2, 6.1, 6.2) 2, What solution components contribute to the tonicity nature of this solution? (Napra 3.2, 6.1, 6.2) 3, What adverse physiological changes can occur if such parenteral admixture is infused into the blood circulation of a patient? (Napra 3.2)
Case Study Importance of Osmolarity/Osmolality
Helen has prepared 1000 mL of an IV infusion solution that contains a number of components such as electrolytes, a medication, and a buffering agent to ensure a pH close to that of blood. This preparation has an osmolality of 600 mOsmol/kg. Note that preparations that are isotonic have an osmolality close to that of blood (i.e., 285–295 mOsm/kg).
1, What is the tonicity nature of this solution? Why?
- Isotonic
- Hypertonic
- Hypotonic
(Napra 3.2, 6.1, 6.2)
2, What solution components contribute to the tonicity nature of this solution? (Napra 3.2, 6.1, 6.2)
3, What adverse physiological changes can occur if such parenteral admixture is infused into the blood circulation of a patient? (Napra 3.2)
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