Frog muscle cells and the solution bathing the cells contain ions at different concentrations. The concentrations of Na+, Ca²+, K+ and Cl¯ are shown in the table. The temperature is 25 °C. ion intracellular concentration (MM) extracellular concentration Answer: -0.0704 Na+ 12 120 Ca²+ 1 x 10-4 3 V K+ ◆ 155 10 CI- (MM) The resting frog muscle membrane potential is determined by the equilibrium of K+ across the cell membrane. What is the voltage inside the frog cell if the outside solution is at zero volts? 4 62

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Frog muscle cells and the solution bathing the cells contain ions at different
concentrations. The concentrations of Na+, Ca²+, K+ and Cl¯ are shown in the table. The
temperature is 25 °C.
ion
intracellular concentration
(MM)
extracellular concentration
Answer: -0.0704
Na+
12
120
Ca²+
1 x 10-4
3
K+
155
V
10
CI-
4
(MM)
The resting frog muscle membrane potential is determined by the equilibrium of K+ across
the cell membrane. What is the voltage inside the frog cell if the outside solution is at
zero volts?
62
Transcribed Image Text:Frog muscle cells and the solution bathing the cells contain ions at different concentrations. The concentrations of Na+, Ca²+, K+ and Cl¯ are shown in the table. The temperature is 25 °C. ion intracellular concentration (MM) extracellular concentration Answer: -0.0704 Na+ 12 120 Ca²+ 1 x 10-4 3 K+ 155 V 10 CI- 4 (MM) The resting frog muscle membrane potential is determined by the equilibrium of K+ across the cell membrane. What is the voltage inside the frog cell if the outside solution is at zero volts? 62
Expert Solution
Step 1: Introduction

Inside the cell, the most abundant ions is K+ (potassium). Therefore for the calculation of membrane potential inside the cell, potassium ions concentration is necessary. 

The membrane potential can be calculated ny using Nernst's equation which is given below. 

E space equals fraction numerator R T over denominator n F end fraction space cross times space ln subscript e space left square bracket K to the power of plus right square bracket subscript o u t s i d e end subscript over left square bracket K to the power of plus right square bracket subscript i n s i d e end subscript space space space space comma space w h e r e
space space
R space equals space G a s space c o n s tan t space equals space 8.314 space J divided by m o l
T space equals space T e m p e r a t u r e space equals space 25 degree C space equals space 298 K
n equals space e l e m e n t a r y space c h a r g e space left parenthesis f o r space K to the power of plus space comma space n space equals space 1 right parenthesis
F space equals space F a r a d a y apostrophe s space c o n s tan t space equals space 96500 space C

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