ferR ferP. ferS ferI ferZ KEY: O = operator P = promoter Boxes = structural genes Arrows = transcription start sites A hypothetical operon is shown above. At high iron levels, ferR binds a molecule of iron and the complex then binds the fer operator and prohibits transcription. When iron levels are low, the molecule of iron bound to ferR is used, which causes a conformational change so that ferR is released from the operator. a. Trypotphan is the effector molecule in the trp operon. What would be the equivalent molecule in this operon? b. Under what environmental condition will ferR be bound to the operator: high iron or low iron? c. Complete the table as to the expected transcription of different genotypes in high and low iron concentrations. yes = transcription, no = no transcription transcription of the ferP-ferZ genes in high iron? Genotype in genome low iron? Wild-type Nonfunctional ferR mutant fer operator

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Hypothetical Operon Model**

**Diagram Explanation:**
The diagram illustrates a hypothetical operon with several components:

- **Key:**
  - **O** = Operator
  - **P** = Promoter
  - **Boxes** = Structural genes
  - **Arrows** = Transcription start sites

- **Operon Structure**: This operon includes a promoter (P), operator (O), and several structural genes labeled as ferR, ferP, ferS, ferT, and ferZ.

**Operon Function:**

A hypothetical operon is depicted above. At high iron levels, ferR binds a molecule of iron, and the complex binds the fer operator, inhibiting transcription. When iron levels are low, the iron molecule bound to ferR is consumed, causing a conformational change that releases ferR from the operator.

**Questions:**

a. Tryptophan is the effector molecule in the trp operon. What would be the equivalent molecule in this operon?

b. Under what environmental condition will ferR be bound to the operator: high iron or low iron?

c. Complete the table as to the expected transcription of different genotypes in high and low iron concentrations. 

**Transcription Table:**

- **Yes** = Transcription
- **No** = No Transcription

| Genotype in Genome       | Transcription of the ferP-ferZ Genes in High Iron? | Low Iron? |
|--------------------------|---------------------------------------------------|-----------|
| Wild-type                |                                                   |           |
| Nonfunctional ferR       |                                                   |           |
| Mutant fer operator      |                                                   |           |

*Note: Please fill in the table based on your understanding of the operon model and given instructions.*
Transcribed Image Text:**Hypothetical Operon Model** **Diagram Explanation:** The diagram illustrates a hypothetical operon with several components: - **Key:** - **O** = Operator - **P** = Promoter - **Boxes** = Structural genes - **Arrows** = Transcription start sites - **Operon Structure**: This operon includes a promoter (P), operator (O), and several structural genes labeled as ferR, ferP, ferS, ferT, and ferZ. **Operon Function:** A hypothetical operon is depicted above. At high iron levels, ferR binds a molecule of iron, and the complex binds the fer operator, inhibiting transcription. When iron levels are low, the iron molecule bound to ferR is consumed, causing a conformational change that releases ferR from the operator. **Questions:** a. Tryptophan is the effector molecule in the trp operon. What would be the equivalent molecule in this operon? b. Under what environmental condition will ferR be bound to the operator: high iron or low iron? c. Complete the table as to the expected transcription of different genotypes in high and low iron concentrations. **Transcription Table:** - **Yes** = Transcription - **No** = No Transcription | Genotype in Genome | Transcription of the ferP-ferZ Genes in High Iron? | Low Iron? | |--------------------------|---------------------------------------------------|-----------| | Wild-type | | | | Nonfunctional ferR | | | | Mutant fer operator | | | *Note: Please fill in the table based on your understanding of the operon model and given instructions.*
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