During positive selection, if the selecting MHC molecule is class I, then a. gene expression of CD8 is halted b. the thymocyte is committed to the CD8 lineage c. continued α-chain rearrangement occurs on the other locus to produce a mature T cell with two receptors d. the thymocyte differentiates into a CD4 T cell e. gene expression of CD4 is enhanced.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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During positive selection, if the selecting MHC molecule is class I, then
a. gene expression of CD8 is halted
b. the thymocyte is committed to the CD8 lineage
c. continued α-chain rearrangement occurs on the other locus to produce a mature T cell with two receptors
d. the thymocyte differentiates into a CD4 T cell
e. gene expression of CD4 is enhanced.
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