;, Consider a spherical cell at body temperature (37°C) that is 10 µm in radius. The concentration of ions inside and outside the cell are given below. Sodium and potassium are the only permeant ions, and the membrane contains proteins that pump in 3 sodium ions for every 2 potassium ions pumped out. [Na*] = ? [K*] = 119mM [CI] = 8mM [A] = 121mM [Na'] = 120mM [K'] = ? [CI]] = 125mM [glu] = ? (a) Suppose the cell is in osmotic equilibrium, find the 3 unknown concentrations. (b) Sunnose the membrane conductance to sodium is 5% that to notassium find the resting membrane notential

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;, Consider a spherical cell at body temperature (37°C) that is 10 µm in radius. The concentration of ions inside
and outside the cell are given below. Sodium and potassium are the only permeant ions, and the membrane
contains proteins that pump in 3 sodium ions for every 2 potassium ions pumped out.
[Na*] = ?
[K*] = 119mM
[Ci] = 8mM
[A] = 121mM
[Na*] = 120mM
[K*] = ?
[Cr] = 125MM
[glu] = ?
(a) Suppose the cell is in osmotic equilibrium, find the 3 unknown concentrations.
(b) Suppose the membrane conductance to sodium is 5% that to potassium, find the resting membrane potential
via circuit analysis.
(c) What would the resting potential be if the membrane were instead permeable only to chloride ions?
(d) Suppose the cell was suddenly placed in distilled water, what would happen to it? And, how much external
pressure (positive or negative) would be needed to prevent this from happening?
Transcribed Image Text:;, Consider a spherical cell at body temperature (37°C) that is 10 µm in radius. The concentration of ions inside and outside the cell are given below. Sodium and potassium are the only permeant ions, and the membrane contains proteins that pump in 3 sodium ions for every 2 potassium ions pumped out. [Na*] = ? [K*] = 119mM [Ci] = 8mM [A] = 121mM [Na*] = 120mM [K*] = ? [Cr] = 125MM [glu] = ? (a) Suppose the cell is in osmotic equilibrium, find the 3 unknown concentrations. (b) Suppose the membrane conductance to sodium is 5% that to potassium, find the resting membrane potential via circuit analysis. (c) What would the resting potential be if the membrane were instead permeable only to chloride ions? (d) Suppose the cell was suddenly placed in distilled water, what would happen to it? And, how much external pressure (positive or negative) would be needed to prevent this from happening?
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