what would the membrane potential be if the membrane became 10X more permeable to both sodium and chloride Ionic Composition Inside and Outside a Typical Mammalian CellIntracellularComponent Concentration (mm)CationsNa+K+Mg2+Ca²+H+AnionsCI-101450.51 x 10-47 x 105 (pH = 7.2)10ExtracellularConcentration (mm)1505214 x 10-5 (pH = 7.4)110Relative Permeability0.021.000.50

When the membrane becomes 10 times more permeable to sodium (Na⁺) and chloride (Cl⁻) ions:Sodium ions (Na⁺) will flow into the cell due to their electrochemical gradient, tending to depolarize the cell (make the interior less negative).Chloride ions (Cl⁻) may tend to move out of the cell, but because the resting membrane potential is close to the chloride equilibrium potential, its impact might be less significant. However, it might slightly contribute to hyperpolarization (making the interior more negative).Given the increased permeability to sodium and to a lesser extent chloride:Sodium influx will have a more pronounced effect, tending to depolarize the cell, moving the membrane potential closer to the equilibrium potential for sodium (+60 mV).Chloride's movement may slightly counteract the depolarization due to its tendency to move out, possibly nudging the potential towards the chloride equilibrium potential (-70 mV).If the membrane becomes 10 times more permeable to sodium and chloride ions, the overall effect would likely be a shift toward a less negative membrane potential (depolarization), primarily influenced by the increased sodium permeability, possibly reaching closer to the equilibrium potential for sodium, which is around +60 mV.

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Anatomy and Physiology

what would the membrane potential be if the membrane became 10X more permeable to both sodium and chloride

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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