PeptiDream has developed a technology to create cyclic peptides. Which of the following is TRUE about the technology they developed? O They adopted Antisense Technology to incorporate cyclic peptides to the antisense drug which has improved therapeutic effect. O They utilized HTPathwaySeq, which is an RNA-seq based drug screening platform to characterize therapeutic molecules including cyclic peptides O They combine the technology of mRNA display and Flexizyme to put an unnatural amino acid onto a tRNA which goes into the in vitro translation system O They took advantage of the SYNTHORUNTM Technology Platform, which expands the genetic code by adding a new DNA base pair in order to incorporate unnatural amino acid.

Q: • Using the RNA base abbreviations hairpin structure below which would allow a stable hairpin to…

A: DNA is usually present as double-stranded molecules. The A-, B-, and Z-form of DNA are the three…

Q: CONTROL   Baseline Amiloride Forskolin Inh172 Vte (mV) -78 -2 -4 -3 DVRt (mV) 8 16 7.5…

A: To calculate the current flowing through ENaC and CFTR for both vectors, we need to use the values…

Q: Identify the experimental techniques used to study protein targeting.

A: Protein targeting is the process by which proteins are directed to specific cellular compartments or…

Q: You are employed in a gene therapy laboratory to test the effectiveness of a vector for correcting…

A: Cystic Fibrosis Transmembrane Conductance Regulator is referred to as CFTR. It is a protein that is…

Q: What are the advantages of the yeast-two-hybrid system over other in vitro methods used for…

A: The yeast -two- hybrid system is the  In - Vivo identification technique of protein interaction in…

Q: CRISPR has been well and truly deployed in the fight against COVID-19, but what potential does it…

A: It is a powerful technology for editing gene functions, alter the DNA sequences, and modify the…

Q: Discuss the possible advantages of quorum sensingproteins as antibiotic targets

A: Quorum sensing enables the bacteria to detect and respond to the cell population density by gene…

Q: Place the stages of a CRISPR-cas9 gene editing workflow in the correct order (there is one incorrect…

A: CRISPR is a tool that is used to edit DNA (and, recently, RNA).

Q: Drawbacks of biotechnology in bullets point.

A: Biotechnology is the branch of biology that aims at developing products useful for mankind by using…

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A: The enzyme is a class of protein except for ribozymes (class of RNA) increase the rate of the…

Q: Here is a list of knockout gene mutations that are desired to make in E. coli genome. You should…

A: A number of knockout gene mutations in the E. coli genome are shown to us in this scenario. Each…

Q: What would likely result from a mutation in the lac operon promoter that increases the number of RNA…

A: RNA polymerase is the enzyme that polymerises messenger RNA (mRNA) over the DNA molecule. This…

Q: You are assigned to create new MRNA vaccine. You identified target protein (gene) for vaccine and…

A: An mRNA vaccine uses a type of mRNA to induce an immune response in the body example COVID vaccine…

Q: hat is the similarity of experimen vitamin c assay and the clearance of a molecule like glucose by…

A: A vitamin assay is the measurement of the activity or presence of a specific component in a specific…

Q: 1. Your company plans to develop two monoclonal antibodies in mice against Spike (S) proteins of…

A: The current Covid-19 epidemic has increased interest in creating mAbs that focus on the virus' Spike…

Q: What if you designed a CRISPR/cas9 assay for a gene knockout, but there's no PAM sequence…

A: CRISPR is a group of DNA sequences present in the genomes of bacteria and archaea, which are…

Q: Present an overview of RNA interference (RNAi). How does the silencing process begin, and what major…

A: RNA interference is characterized by inhibition of the gene expression by the RNA molecule. This…

Q: You have identified a mutation. In the normal organism the DNA TEMPLATE strand is 5'AGT3' in the…

A: Mutations are changes in the sequence of DNA which may or may not affect the phenotype of the…

Q: What does MEGA stand for and what is this assay used to determine? How to do perform the assay?

A: Many assisted reproductive techniques are widely used around the globe.

Q: You are employed in a gene therapy laboratory to test the effectiveness of a vector for correcting…

A: Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations can be fixed using the…

Q: What is the size of the current that flows through ENaC for both vectors? Control:  97mA.cm2…

A: CFTR stands for Cystic Fibrosis Transmembrane Conductance Regulator. It is a protein that is…

Q: Site directed mutagenesis is used to: 1.determine the critical base per sequences in a Genome 2.…

A: DNA consists of double strands of sequentially arranged nucleotides. The nucleotide sequence present…

Q: BugRx is a new biotechnology company in Cambridge, Massachusetts, developing human monoclonal…

A: One possible PK protocol to study the distribution of the antibody to Factor 801A after IP injection…

Q: Why is phospholipase c is the target on this western blot explain in detail

A: Phospholipase C (PLC) is an enzyme that cleaves the phospholipids just before the attachment of…

Q: below One common structure found in "folded" SSRNA is a • Using the RNA base abbreviations: A, G, C…

A: Stem-loop is the structure formed by single-stranded RNA (ribonucleic acid) when nucleotides base…

Q: Microarrays are often used to monitor the RNA level of a large number of genes in an organism or…

A: A microarray is a powerful technology used in molecular biology and genomics to simultaneously…

Q: What are the major components of the CRISPR-Cas9 system? What mechanism does it employ to combine…

A: CRISPR-Cas9 is system is a gene editing technology involves mainly two essential components. One is…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.