A RFLP is discovered that is linked to the gene for Duchenne’s muscular dystrophy (DMD). DMD is an X-linked, recessive trait. The RFLP is 2 map units from the gene for DMD. Consider the following pedigree and Southern blot using a probe that hybridizes to the RFLP. Which band/s is/are associated with DMD?What is the genotype for individuals 3 and 4? (Remember, this is an X linked disease, so use X’s and Y’s to denote).Individual 9 married a man who does NOT have muscular dystrophy, and she is pregnant. DMD is an X-linked trait. What is the probability for their child to have DMD? An amniocentesis is performed and it is determined that 9’s child in utero has only a 10 kb band that hybridizes to the same probe used above. What can you say about the child now? 5 6 7810kbSkb2kb2 35600

Name: A RFLP is discovered that is linked to the gene for Duchenne’s muscula
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Description: A RFLP is discovered that is linked to the gene for Duchenne’s muscular dystrophy (DMD). DMD is an X-linked, recessive trait. The RFLP is 2 map units from the gene for DMD. Consider the following pedigree and Southern blot using a probe that hybridiz

RFLP (Restriction Fragment length polymorphism) : RFLP (Restriction Fragment length polymorphism is…

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Human Anatomy & Physiology (11th Edition)

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Author:Elaine N. Marieb, Katja N. Hoehn

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A RFLP is discovered that is linked to the gene for Duchenne’s muscular dystrophy (DMD). DMD is an X-linked, recessive trait. The RFLP is 2 map units from the gene for DMD. Consider the following pedigree and Southern blot using a probe that hybridizes to the RFLP.

Which band/s is/are associated with DMD?
What is the genotype for individuals 3 and 4? (Remember, this is an X linked disease, so use X’s and Y’s to denote).
Individual 9 married a man who does NOT have muscular dystrophy, and she is pregnant. DMD is an X-linked trait. What is the probability for their child to have DMD?
An amniocentesis is performed and it is determined that 9’s child in utero has only a 10 kb band that hybridizes to the same probe used above. What can you say about the child now?

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