A doctoral student in biology, Esther Mensah, is reviewing primary literature over RNAi interference as part of her literary research for her proposal on decreasing the amount of abnormal white blood cell growth associated with acute myeloid leukemia (AML) using a murine (mouse) model. She is being provided with 10 AML mice courtesy of her mentor. Can you help her out with her proposal? 1) Given her knowledge of RNAi, what type of RNA will Esther use to target the murine AML gene? apiRNA.bcircRNA.clncRNA.dsiRNA. 2) In order for Esther’s RNAi to work, the small RNA pieces have to interact with another molecule. What molecule does she hope it will bind to?aDUH! It will bind to the DNA strands of the AML gene and knock it out!bIt will bind to tRNA, which will block attachment of the amino acids needed to make the AML protein.cIt will bind to circRNA, which will increase its longevity.dIt will bind to the mRNA of the AML gene.

Gene expression describes the transformation of genetic information contained in a gene into a…

Answered: A doctoral student in biology, Esther…

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter16: Gene Expression

Section: Chapter Questions

Problem 38CTQ: A scientist discovers a virus encoding a Protein X that degrades a subunit of the elF4F complex....

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A doctoral student in biology, Esther Mensah, is reviewing primary literature over RNAi interference as part of her literary research for her proposal on decreasing the amount of abnormal white blood cell growth associated with acute myeloid leukemia (AML) using a murine (mouse) model. She is being provided with 10 AML mice courtesy of her mentor. Can you help her out with her proposal?

Given her knowledge of RNAi, what type of RNA will Esther use to target the murine AML gene?

piRNA.

circRNA.

lncRNA.

siRNA.

In order for Esther’s RNAi to work, the small RNA pieces have to interact with another molecule. What molecule does she hope it will bind to?

DUH! It will bind to the DNA strands of the AML gene and knock it out!

It will bind to tRNA, which will block attachment of the amino acids needed to make the AML protein.

It will bind to circRNA, which will increase its longevity.

It will bind to the mRNA of the AML gene.

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