A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving seven participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later. Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance. Use the 6 steps of hypothesis testing. Data (as shown below) are provided in untreated.sas7bdat with variables subject, SBP_Baseline, and SBP_4_weeks Baseline: 120 145 130 160 152 143 126 4 Weeks: 122 142 135 158 155 140 130

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Six Sigma

Six Sigma’s usage for measurement standards goes back to Carl Friedrich Gauss, 1855, when the normal curve concept was introduced.

Quality Control

Quality Management System (QMS), Quality Assurance (QA) and Quality Control (QC) are part of Quality umbrella.