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6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis. Ferritin A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein? B. How is activity of the IRE binding protein regulated? C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain. Explanation Transferrin receptor RNA levels ( ) high ( ) low ( ) high ( ) low Protein levels () high levels ( ) low levels () high levels ( ) low levels

6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis. Ferritin A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein? B. How is activity of the IRE binding protein regulated? C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain. Explanation Transferrin receptor RNA levels ( ) high ( ) low ( ) high ( ) low Protein levels () high levels ( ) low levels () high levels ( ) low levels

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Vampire Bats and Iron Homeostasis** **6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis.** **A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein?** (Provide space for a detailed explanation) **B. How is activity of the IRE binding protein regulated?** (Provide space for a detailed explanation) **C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain.** | | RNA levels | Protein levels | Explanation | |---------------------|---------------------------|---------------------------|---------------------------| | **Ferritin** | ( ) high | ( ) high levels | (Provide specific explanation) | | | ( ) low | ( ) low levels | | | **Transferrin receptor** | ( ) high | ( ) high levels | (Provide specific explanation) | | | ( ) low | ( ) low levels | | This section discusses the role of iron regulation in vampire bats' physiology, focusing on the function of the IRE binding protein and genetic expression in adaptation to high iron diets. Use the table to hypothesize mRNA and protein levels in response to iron abundance.
Transcribed Image Text:**Vampire Bats and Iron Homeostasis** **6. Vampire bats are mammals that consume blood as their only source of nutrients. Because blood is rich in iron, it is necessary for the digestive system of the vampire bat to manage excess iron. Like humans, ferritin and transferrin receptor gene products are expressed by the vampire bat genome and function to maintain iron homeostasis.** **A. The iron response element (IRE) binding protein is able to regulate expression of both ferritin and transferrin receptor genes. What feature of these genes allows for specific regulation by the IRE binding protein?** (Provide space for a detailed explanation) **B. How is activity of the IRE binding protein regulated?** (Provide space for a detailed explanation) **C. In an environment with excess iron, what levels of mRNA and protein do you expect to detect of Ferritin and Transferrin receptor? Briefly explain.** | | RNA levels | Protein levels | Explanation | |---------------------|---------------------------|---------------------------|---------------------------| | **Ferritin** | ( ) high | ( ) high levels | (Provide specific explanation) | | | ( ) low | ( ) low levels | | | **Transferrin receptor** | ( ) high | ( ) high levels | (Provide specific explanation) | | | ( ) low | ( ) low levels | | This section discusses the role of iron regulation in vampire bats' physiology, focusing on the function of the IRE binding protein and genetic expression in adaptation to high iron diets. Use the table to hypothesize mRNA and protein levels in response to iron abundance.
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