Many genes whose expression is turned on by DNAdamage have been isolated. Loss-of-function mutations in the lexA gene lead to the expression of manyof these genes, even when there has been no DNAdamage. Would you hypothesize that LexA protein isa positive or a negative regulator? Why?
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
Many genes whose expression is turned on by DNA
damage have been isolated. Loss-of-function mutations in the lexA gene lead to the expression of many
of these genes, even when there has been no DNA
damage. Would you hypothesize that LexA protein is
a positive or a negative regulator? Why?
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