6. Give the name of the disease that is causing the baby's symptoms. Explainwhy the symptoms are worse between meals. Are there any otherbiochemical changes you might expect in addition to this? A baby fails to thrive after 8 weeks of life. She wakes frequently and is very irritable.The parents notice that the baby appears to be better after feeding but that herabdomen is protruding more and more. After her condition worsens, she is admittedto hospital where an examination indicates that his liver and kidneys areenlarged. A liver biopsy was performed and a liver extract was prepared byhomogenising 200mg of liver in 1ml of 0.3M sucrose, 10mM Tris-HCl, pH 7.5, 1mMdithiothreitol, 1mM EGTA and 100μM phenylmethylsulphonyl fluoride (PMSF). Theactivity of enzyme X was measured in the liver sample by adding 100μl of the liverextract to 0.9 ml of 120mM Imidazole buffer (pH 7.0) containing 2.4mM NAD+, 30mMglucose-6-phosphate, 6 units/ml of glucose dehydrogenase in a cuvette with a 1cmlight path. The increase in absorbance at 340nm was followed over a period of 10minutes and compared with a blank sample containing everything but the glucose-6-phosphate. The results are shown in the table below:Time(mins)0246810Absorbance at 340nmWith G6P00.120.230.340.440.53Without G6P00.030.0620.0820.0870.092

Glucose dehydrogenase is an enzyme that is involved in the pentose phosphate pathway that catalyzes…

Answered: 6. Give the name of the disease that is…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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12. A protein whose structure is altered to the point that its activity is destroyed is said tobe-----------------------------.
D
6. Miraculin is a protein isolated from what is known as the "miracle berry," the fruit of a plant native to West Africa. It is described as 'miraculous' because the protein is able to alter our sense of taste. When introduced into the mouth, this protein interacts with the taste buds and makes normally sour foods taste extremely sweet-imagine biting into a lemon and tasting lemonade instead of burning acid. Researchers have created an in vitro system to test the function of this protein. Cultured cells expressing TIR2/T1R3 receptors (those that normally detect sweet taste) were tested with or without miraculin and at neutral and low pHs. Results from this experiment showing the level of sweet detection in these different treatments appear below. From these data, make conclusions about how miraculin works to affect taste. Be sure to explain your answer mechanistically. Treatment Neutral pH Low pH Sugar alone Miraculin + Sugar Miraculin alone normal detection normal detection low…
3. Give the pharmacological property of the following terpenes/terpenoids. Where do they naturally occur? a. saponins b. terpenoids c. cardiac glycosides 4. How can terpenes/terpenoids be extracted from plants. What are the chemical tests used in identifying the presence of cardiac glycosides?
32. Although protein denaturation causes the loss of a biological function of a protein, it actually helps improving the functionality of a protein in food systems. Walaupun denaturasi protein menyebabkan kehilangan fungsi biologi protein, ia sebenarnya membantu meningkatkan kefungsian protein dalam sistem makanan. a) What does it mean by protein denaturation? / Apakah yang dimaksudkan b) Explain how protein can be denatured. / dengan denaturasi protein? Terangkan bagaimana protein boleh didenaturasi.
3. Explain how water activity and pH can affect the susceptibility of proteins to denaturation by heat.
4. Ensuring adequate maternal intake of a spe- cific nutrient is especially important in reduc- ing the incidence of the congenital anomaly shown in the image. A deficiency of this nu- trient, when present in an adult, is associated with which of the following conditions? Subarachnoid space (A) Confabulation and anterograde amnesia (B) Diarrhea, dermatitis, and dementia (C) Megaloblastic anemia (D) Megaloblastic anemia with neurologic symptoms (E) Microcytic anemia (F) Polyneuritis and cardiac pathology (G) Swollen and bleeding gums, easy bruising, and poor wound healing HELR
6. The qualitative tests for determination of a-amino acids (ninhydrin test, xanthoproteic test, Millon's test, Foli's test) and identification of peptide bond by the biuret test wwwwwwwwww
9. A daily diet of a 55-ycar-old woman, consisted of a 500 g of carbohydrates, 100 g of animal fats and 150 g of proteins, at the background of low physical activity. What possible consequences for the lipid metabolism such lifestyle could trigger? For the answer: a) compare the daily food consumption of the patient with the norm for this age and level of physical activity; b) draw the scheme of TAG synthesis in the liver and continue with their following transport to the tissues; c) draw the scheme of metabolic pathways which are more active in adipocytes of this patient compared with an individual of the same age consuming balanced dict; d) name the biologically active molecules released by adipocytes of this patient.
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6. Give the name of the disease that is causing the baby's symptoms. Explain why the symptoms are worse between meals. Are there any other biochemical changes you might expect in addition to this?